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Gene Expression Data
Assay Details
Assay
Reference: J:184936 Unni DK, et al., Multiple Slits regulate the development of midline glial populations and the corpus callosum. Dev Biol. 2012 May 1;365(1):36-49
Assay type: Immunohistochemistry
MGI Accession ID: MGI:6285530
Gene symbol: Gap43
Gene name: growth associated protein 43
Antibody: anti-GAP43
Results
Specimen 4A: embryonic day 17.5 (more )
Structure Level Pattern Image Note
TS25: corpus callosum Present Regionally restricted 4A Callosal axons traverse cortical midline.
Specimen 4B: embryonic day 17.5 (more )
Structure Level Pattern Image Note
TS25: corpus callosum Present Regionally restricted 4B Callosal axons traverse cortical midline.
Specimen 4C: embryonic day 17.5 (more )
Structure Level Pattern Image Note
TS25: corpus callosum Present Regionally restricted 4C
Specimen 4D: embryonic day 17.5; Slit1tm1.1Matl/Slit1tm1.1Matl (more )
Structure Level Pattern Image Note
TS25: corpus callosum Present Regionally restricted 4D Callosal axons traverse cortical midline.
Specimen 4E: embryonic day 17.5; Slit1tm1.1Matl/Slit1tm1.1Matl (more )
Structure Level Pattern Image Note
TS25: corpus callosum Present Regionally restricted 4E Callosal axons traverse cortical midline.
Specimen 4F: embryonic day 17.5; Slit1tm1.1Matl/Slit1tm1.1Matl (more )
Structure Level Pattern Image Note
TS25: corpus callosum Present Regionally restricted 4F Callosal axons traverse cortical midline.
Specimen 4G: embryonic day 17.5; Slit2tm1Matl/Slit2tm1Matl (more )
Structure Level Pattern Image Note
TS25: corpus callosum Present Regionally restricted 4G Callosal axons traverse cortical midline.
TS25: telencephalon septum Present Regionally restricted 4G Subpopulation of callosal axons ectopically entered septum.
Specimen 4H: embryonic day 17.5; Slit2tm1Matl/Slit2tm1Matl (more )
Structure Level Pattern Image Note
TS25: corpus callosum Present Regionally restricted 4H Callosal axons traverse cortical midline.
TS25: telencephalon septum Present Regionally restricted 4H Subpopulation of callosal axons ectopically entered septum.
Specimen 4I: embryonic day 17.5; Slit2tm1Matl/Slit2tm1Matl (more )
Structure Level Pattern Image Note
TS25: corpus callosum Present Regionally restricted 4I Callosal axons traverse cortical midline.
TS25: telencephalon septum Present Regionally restricted 4I Subpopulation of callosal axons ectopically entered septum.
Specimen 4J: embryonic day 17.5 (more )
Structure Level Pattern Image Note
TS25: corpus callosum Present Regionally restricted 4J In approximately 30% of mutant mice, axons in rostral region of corpus callosum failed to cross midline.
Specimen 4K: embryonic day 17.5 (more )
Structure Level Pattern Image Note
TS25: corpus callosum Present Regionally restricted 4K Disrupted axons in in dorsal portion of corpus callosum at middle levels.
Specimen 4L: embryonic day 17.5 (more )
Structure Level Pattern Image Note
TS25: corpus callosum Present Regionally restricted 4L
Specimen 5A: embryonic day 17.5 (more )
Structure Level Pattern Image Note
TS25: corpus callosum Present Regionally restricted 5A Callosal axons traverse cortical midline.
Specimen 5B: embryonic day 17.5 (more )
Structure Level Pattern Image Note
TS25: corpus callosum Present Regionally restricted 5B Callosal axons traverse cortical midline.
Specimen 5C: embryonic day 17.5 (more )
Structure Level Pattern Image Note
TS25: corpus callosum Present Regionally restricted 5C Callosal axons traverse cortical midline.
Specimen 5D: embryonic day 17.5; Slit1tm1.1Matl/Slit1tm1.1Matl, Slit3tm1.1Dor/Slit3+ (more )
Structure Level Pattern Image Note
TS25: corpus callosum Present Regionally restricted 5D Callosal axons traverse cortical midline - 4 of 14 embryos showed a mild phenotype.
Specimen 5E: embryonic day 17.5; Slit1tm1.1Matl/Slit1tm1.1Matl, Slit3tm1.1Dor/Slit3+ (more )
Structure Level Pattern Image Note
TS25: corpus callosum Present Regionally restricted 5E Callosal axons traverse cortical midline - 4 of 14 embryos showed a mild phenotype.
Specimen 5F: embryonic day 17.5; Slit1tm1.1Matl/Slit1tm1.1Matl, Slit3tm1.1Dor/Slit3+ (more )
Structure Level Pattern Image Note
TS25: corpus callosum Present Regionally restricted 5F Callosal axons traverse cortical midline - 4 of 14 embryos showed a mild phenotype.
Specimen 5G: embryonic day 17.5; Slit1tm1.1Matl/Slit1tm1.1Matl, Slit3tm1.1Dor/Slit3tm1.1Dor (more )
Structure Level Pattern Image Note
TS25: corpus callosum Present Regionally restricted 5G Axons in rostral region of corpus calloxum failed to cross midline.
Specimen 5H: embryonic day 17.5; Slit1tm1.1Matl/Slit1tm1.1Matl, Slit3tm1.1Dor/Slit3tm1.1Dor (more )
Structure Level Pattern Image Note
TS25: corpus callosum Present Regionally restricted 5H Axons in dorsal portion of corpus callosum at middle levels were disrupted.
Specimen 5I: embryonic day 17.5; Slit1tm1.1Matl/Slit1tm1.1Matl, Slit3tm1.1Dor/Slit3tm1.1Dor (more )
Structure Level Pattern Image Note
TS25: corpus callosum Present Regionally restricted 5I
Specimen 5J: embryonic day 17.5; Slit1tm1.1Matl/Slit1tm1.1Matl, Slit2tm1Matl/Slit2+ (more )
Structure Level Pattern Image Note
TS25: corpus callosum Present Regionally restricted 5J Callosal axons traverse cortical midline.
Specimen 5K: embryonic day 17.5; Slit1tm1.1Matl/Slit1tm1.1Matl, Slit2tm1Matl/Slit2+ (more )
Structure Level Pattern Image Note
TS25: corpus callosum Present Regionally restricted 5K Callosal axons traverse cortical midline.
Specimen 5L: embryonic day 17.5; Slit1tm1.1Matl/Slit1tm1.1Matl, Slit2tm1Matl/Slit2+ (more )
Structure Level Pattern Image Note
TS25: corpus callosum Present Regionally restricted 5L Callosal axons traverse cortical midline.
Specimen 5M: embryonic day 17.5; Slit1tm1.1Matl/Slit1tm1.1Matl, Slit2tm1Matl/Slit2tm1Matl (more )
Structure Level Pattern Image Note
TS25: corpus callosum Present Regionally restricted 5M Mice displayed agenesis of corpus callosum, with axons turning away from midline.
Specimen 5N: embryonic day 17.5; Slit1tm1.1Matl/Slit1tm1.1Matl, Slit2tm1Matl/Slit2tm1Matl (more )
Structure Level Pattern Image Note
TS25: corpus callosum Present Regionally restricted 5N Mice displayed agenesis of corpus callosum, with axons turning away from midline.
Specimen 5O: embryonic day 17.5; Slit1tm1.1Matl/Slit1tm1.1Matl, Slit2tm1Matl/Slit2tm1Matl (more )
Structure Level Pattern Image Note
TS25: corpus callosum Present Regionally restricted 5O Mice displayed agenesis of corpus callosum, with axons turning away from midline.
Specimen 10G: embryonic day 16.5 (more )
Structure Level Pattern Image Note
TS24: telencephalon Present Regionally restricted 10G Expression in axons approaching midline.
Specimen 10H: embryonic day 16.5; Slit2tm1Matl/Slit2tm1Matl (more )
Structure Level Pattern Image Note
TS24: telencephalon Present Regionally restricted 10H Expression in axons that are more lateral.
Specimen 10I: embryonic day 16.5; Slit1tm1.1Matl/Slit1tm1.1Matl, Slit2tm1Matl/Slit2tm1Matl (more )
Structure Level Pattern Image Note
TS24: telencephalon Present Regionally restricted 10I Expression in axons that are more lateral.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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03/25/2025
MGI 6.24 		The Jackson Laboratory