Gene Expression Data
Assay Details
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Assay
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Reference:
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J:202339
Sittaramane V, et al., The PCP protein Vangl2 regulates migration of hindbrain motor neurons by acting in floor plate cells, and independently of cilia function. Dev Biol. 2013 Oct 15;382(2):400-12
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Assay type:
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RNA in situ
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MGI Accession ID:
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MGI:6284557
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Gene symbol:
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Tbx20
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Gene name:
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T-box 20
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Probe:
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Tbx20 probe3
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Probe preparation:
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labelled with digoxigenin
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Results
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Specimen
5E/S9A:
embryonic day 12.5; Gli2tm1Alj/Gli2 +
(more  )
Specimen
5E/S9A:
(close  )
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Genetic Background:
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involves: 129S1/Sv * 129X1/SvJ
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Mutant Allele(s):
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Gli2tm1Alj/Gli2+
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Age:
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embryonic day 12.5
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Sex:
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Not Specified
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Type:
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whole mount
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| Structure |
Level |
Pattern |
Image |
Note |
| TS20: medulla oblongata |
Present |
Regionally restricted |
S9A
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5E
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Authors state facial branchiomotor (FBM) neurons migrate caudally from rhombomere 4 into rhombomere 6.
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Specimen
5F/S9B:
(close )
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Genetic Background:
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involves: 129S1/Sv * 129X1/SvJ
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Mutant Allele(s):
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Gli2tm1Alj/Gli2tm1Alj
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Age:
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embryonic day 12.5
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Sex:
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Not Specified
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Type:
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whole mount
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| Structure |
Level |
Pattern |
Image |
Note |
| TS20: medulla oblongata |
Present |
Regionally restricted |
S9B
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5F
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Authors report FBM neurons fail to migrate out of rhombomere 4, and are found in a single cluster fused across the midline.
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Specimen
S9C:
embryonic day 12.5; Gli2tm1Alj/Gli2 +
(more )
Specimen
S9C:
(close )
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Genetic Background:
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involves: 129S1/Sv * 129X1/SvJ
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Mutant Allele(s):
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Gli2tm1Alj/Gli2+
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Age:
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embryonic day 12.5
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Sex:
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Not Specified
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Type:
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section from whole mount
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Embedding:
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Cryosection
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| Structure |
Level |
Pattern |
Image |
Note |
| TS20: medulla oblongata |
Present |
Regionally restricted |
S9C
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Authors state facial branchiomotor (FBM) neurons migrate caudally from rhombomere 4 into rhombomere 6.
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Specimen
S9D:
embryonic day 12.5; Gli2tm1Alj/Gli2 +
(more )
Specimen
S9D:
(close )
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Genetic Background:
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involves: 129S1/Sv * 129X1/SvJ
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Mutant Allele(s):
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Gli2tm1Alj/Gli2+
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Age:
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embryonic day 12.5
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Sex:
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Not Specified
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Type:
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section from whole mount
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Embedding:
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Cryosection
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| Structure |
Level |
Pattern |
Image |
Note |
| TS20: medulla oblongata |
Present |
Regionally restricted |
S9D
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In rhombomere 6, FBM neurons undergo radial migration to the pial surface of the neural tube.
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Specimen
S9E:
(close )
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Genetic Background:
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involves: 129S1/Sv * 129X1/SvJ
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Mutant Allele(s):
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Gli2tm1Alj/Gli2tm1Alj
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Age:
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embryonic day 12.5
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Sex:
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Not Specified
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Type:
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section from whole mount
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Embedding:
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Cryosection
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| Structure |
Level |
Pattern |
Image |
Note |
| TS20: medulla oblongata |
Present |
Regionally restricted |
S9E
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In rhombomere 4, some FBM neurons under radial migration to pial suface of neural tube.
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Specimen
S9F:
(close )
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Genetic Background:
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involves: 129S1/Sv * 129X1/SvJ
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Mutant Allele(s):
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Gli2tm1Alj/Gli2tm1Alj
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Age:
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embryonic day 12.5
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Sex:
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Not Specified
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Type:
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section from whole mount
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Embedding:
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Cryosection
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| Structure |
Level |
Pattern |
Image |
Note |
| TS20: medulla oblongata |
Ambiguous |
Regionally restricted |
S9F
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Authors report FBM neurons fail to migrate out of rhombomere 4.
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Specimen
S9G:
embryonic day 14.5; Gli2tm1Alj/Gli2 +
(more )
Specimen
S9G:
(close )
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Genetic Background:
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involves: 129S1/Sv * 129X1/SvJ
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Mutant Allele(s):
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Gli2tm1Alj/Gli2+
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Age:
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embryonic day 14.5
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Sex:
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Not Specified
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Type:
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whole mount
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Specimen
S9I:
(close )
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Genetic Background:
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involves: 129S1/Sv * 129X1/SvJ
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Mutant Allele(s):
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Gli2tm1Alj/Gli2tm1Alj
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Age:
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embryonic day 14.5
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Sex:
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Not Specified
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Type:
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whole mount
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| Structure |
Level |
Pattern |
Image |
Note |
| TS22: facial ganglion |
Present |
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S9I
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Facial motor nuclei (nVII) are displaced rostrally and reduced in size.
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Analysis Tools