Summary | Mutation origin | Mutation description | Expression | Recombinase activity | Find Mice (IMSR) | References

Symbol:	Clec4fem1(cre)Glass
Name:	C-type lectin domain family 4, member f; endonuclease-mediated mutation 1, Christopher Glass
MGI ID:	MGI:6283832
Synonyms:	Clec4f-cre-tdTomato
Gene:	Clec4f  Location: Chr6:83621524-83633098 bp, - strand  Genetic Position: Chr6, 35.94 cM
Alliance:	Clec4fem1(cre)Glass page

Strain of Origin:

C57BL/6J

Allele Type:    Endonuclease-mediated (Recombinase, Reporter) Mutation:    Insertion   Clec4fem1(cre)Glass expression driven by 1 gene Knock-in expression driven by: Organism Driver Gene Note mouse Clec4f (MGI:1859834)   Mutation details: CRISPR/Cas9 genome editing is used to insert an internal ribosome entry site (IRES) fused to a Cre recombinase sequence, a viral 2A oligopeptide (T2A) that mediates ribosomal skipping, and a tdTomato variant of red fluorescent protein (RFP) sequence into the 3'UTR of the gene. (J:279524)

Activity:	Tissue activity of this recombinase allele
Driver:	Clec4f (mouse) Summary of all recombinase alleles driven by Clec4f. Alliance mouse Clec4f gene page

In Mice Carrying this Mutation:

1 RNA-Seq or microarray experiment(s)

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Clec4f Mutation:	28 strains or lines available

Original:	J:279524 Sakai M, et al., Liver-Derived Signals Sequentially Reprogram Myeloid Enhancers to Initiate and Maintain Kupffer Cell Identity. Immunity. 2019 Sep 26;
All:	10 reference(s)