Tbr1 Immunohistochemistry Gene Expression Assay

Gene Expression Data
Assay Details

Assay

Reference:	J:208031 Croquelois A, et al., Characterization of the HeCo mutant mouse: a new model of subcortical band heterotopia associated with seizures and behavioral deficits. Cereb Cortex. 2009 Mar;19(3):563-75
Assay type:	Immunohistochemistry
MGI Accession ID:	MGI:6282033
Gene symbol:	Tbr1
Gene name:	T-box brain transcription factor 1

Antibody:	anti-Tbr1
Detection system:	Alexa Fluor 594

Results

Specimen 3 Tbr-1-CTRL: postnatal day 6 (more

)

Structure	Level	Pattern	Image	Note
TS28: cerebral cortex	Strong	Regionally restricted	3_Tbr-1-CTRL	Strong expression in deep cortical layers.

Specimen 3 Tbr-1-MUT: postnatal day 6; Eml1^heco/Eml1^heco (more

)

Structure	Level	Pattern	Image	Note
TS28: cerebral cortex	Strong	Regionally restricted	3_Tbr-1-MUT	Strong expression in homotopic cortex. No expression in heterotopic cortex.

Specimen 6A E15 CTRL: embryonic day 15.5 (more

)

Structure	Level	Pattern	Image	Note
TS23: cortical plate	Present		6A E15 CTRL

Specimen 6A E15 MUT: embryonic day 15.5 (more

)

Structure	Level	Pattern	Image	Note
TS23: cortical plate	Present		6A E15 MUT

Specimen 6A E17 CTRL: embryonic day 17.5 (more

)

Structure	Level	Pattern	Image	Note
TS25: cerebral cortex	Present		6A E17 CTRL

Specimen 6A E17 MUT: embryonic day 17.5 (more

)

Structure	Level	Pattern	Image	Note
TS25: cerebral cortex	Present	Diffuse	6A E17 MUT	Authors report more diffuse and wider distribution of expression.
TS25: cerebral cortex intermediate zone	Present		6A E17 MUT	Expressing cells within the intermediate zone.

Specimen 6A E19 CTRL: embryonic day 19.5 (more

)

Structure	Level	Pattern	Image	Note
TS26: cerebral cortex	Present		6A E19 CTRL

Specimen 6A E19 MUT: embryonic day 19.5 (more

)

Structure	Level	Pattern	Image	Note
TS26: cerebral cortex	Present	Diffuse	6A E19 MUT	Authors report more diffuse and wider distribution of expression.
TS26: cerebral cortex intermediate zone	Present		6A E19 MUT	Expressing cells within the intermediate zone.

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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