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Gene Expression Data
Assay Details
Assay
Reference: J:32851 Andermarcher E, et al., Co-expression of the HGF/SF and c-met genes during early mouse embryogenesis precedes reciprocal expression in adjacent tissues during organogenesis. Dev Genet. 1996;18(3):254-66
Assay type: RNA in situ
MGI Accession ID: MGI:6281715
Gene symbol: Met
Gene name: met proto-oncogene
Probe: c-met cDNA1 (clone B.2)
Probe preparation: Antisense labelled with S35 RNA
Visualized with: Autoradiography
Results
Specimen 3C: embryonic day 9.5 (more )
Note: 25-30 somite stage
Structure Level Pattern Image Note
TS15: neural crest Present Regionally restricted 3C Expression at dorsal edge of neuroectoderm (neural tube).
TS15: 1st branchial arch ectoderm Present 3C
TS15: 2nd branchial arch ectoderm Present 3C
TS15: limb ectoderm Present 3C
TS15: hindgut Present 3C

Specimen 4C: embryonic day 9.5 (more )
Note: 25-30 somite stage
Structure Level Pattern Image Note
TS15: neural crest Present Regionally restricted 4C Expression at dorsal edge of neuroectoderm (neural tube).

Specimen 4F: embryonic day 9.5 (more )
Note: 25-30 somite stage
Structure Level Pattern Image Note
TS15: branchial arch ectoderm Strong 4F Strong expression in surface ectoderm covering branchial arches.

Specimen 4I: embryonic day 9.5 (more )
Note: 25-30 somite stage
Structure Level Pattern Image Note
TS15: limb mesenchyme Present 4I Authors report partial overlap in expression with HGF/SF.

Specimen 4K: embryonic day 9.5 (more )
Note: 25-30 somite stage
Structure Level Pattern Image Note
TS15: trunk mesenchyme Present Regionally restricted 4K Expression in region between trunk and limbs, in myogenic cells migrating from somites to limb buds.

Specimen 5B: embryonic day 9.5 (more )
Note: 25-30 somite stage
Structure Level Pattern Image Note
TS15: dermatome Present 5B Expression in all three compartments of somites.
TS15: myotome Present 5B Expression in all three compartments of somites.
TS15: sclerotome Present 5B Expression in all three compartments of somites.
TS15: hindgut Present 5B

Specimen 6b: embryonic day 13.0 (more )
Structure Level Pattern Image Note
TS21: myotome Present 6B
TS21: interstitial vessel Present 6B Expression in arteries (i.e. aorta, arteries of branchial arches, interstitial arteries).
TS21: lobar bronchus epithelium Present 6B
TS21: dorsal root ganglion Absent 6B

Specimen 7B: embryonic day 13.0 (more )
Structure Level Pattern Image Note
TS21: midgut Present 7B
TS21: liver Present Diffuse 7B Very diffuse expression in the liver. Expression localized to hepatocytes.

Specimen E13.0 not shown: embryonic day 13.0 (more )
Structure Level Pattern Image Note
TS21: trunk musculature Present Regionally restricted Expression in longitudinal dorsal muscles.


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
03/18/2025
MGI 6.24
The Jackson Laboratory