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Gene Expression Data
Assay Details
Assay
Reference: J:170581 Kwon HJ, et al., Radial glia regulate Cajal-Retzius cell positioning in the early embryonic cerebral cortex. Dev Biol. 2011 Mar 1;351(1):25-34
Assay type: Immunohistochemistry
MGI Accession ID: MGI:6281168
Gene symbol: Reln
Gene name: reelin
Antibody: Anti-Reelin
Detection system: Secondary antibody coupled to Cy3
Results
Specimen 1C': embryonic day 15.0; Itgb1tm1Mll/? (more )
Note: Double labeled: red - Reln; green - Calb2 (assay MGI:6281165). Controls were either homozygous animals without cre, or heterozygotes with cre.
Structure Level Pattern Image Note
TS23: cerebral cortex marginal layer Present 1C'' , 1C' Expression was in Cajal-Retzius cells.
Specimen 1D': embryonic day 15.0; Itgb1tm1Mll/Itgb1tm1Mll, Emx1tm1(cre)Krj/Emx1+ (more )
Note: Conditional mutant. Double labeled: red - Reln; green - Calb2 (assay MGI:6281165).
Structure Level Pattern Image Note
TS23: cerebral cortex Present 1D' , 1D'' Ectopic Cajal-Retzius cells were double stained with Calb2 and Reln.
TS23: cerebral cortex marginal layer Present 1D' , 1D'' Normally placed Cajal-Retzius cells were double stained with Calb2 and Reln.
Specimen 3A: embryonic day 15.5; Itgb1tm1Mll/? (more )
Note: Double labeled: red - Reln; green - Laminin. Controls were either homozygous animals without cre, or heterozygotes with cre.
Structure Level Pattern Image Note
TS23: cerebral cortex marginal layer Present 3A'' , 3A Expression was in Cajal-Retzius cells.
Specimen 3B: embryonic day 15.5; Itgb1tm1Mll/Itgb1tm1Mll, Emx1tm1(cre)Krj/Emx1+ (more )
Note: Conditional mutant. Double labeled: red - Reln; green - Laminin.
Structure Level Pattern Image Note
TS23: cerebral cortex Present 3B , 3B'' Expression was in Cajal-Retzius cells, which were displaced in the mutant.
Specimen 3C: embryonic day 15.5; Itgb1tm1Mll/? (more )
Note: Double labeled: red - Reln; green - Cxcl12 (assay MGI:6281172). Controls were either homozygous animals without cre, or heterozygotes with cre.
Structure Level Pattern Image Note
TS23: cerebral cortex marginal layer Present 3C , 3C'' Expression was in Cajal-Retzius cells.
Specimen 3D: embryonic day 15.5; Itgb1tm1Mll/Itgb1tm1Mll, Emx1tm1(cre)Krj/Emx1+ (more )
Note: Conditional mutant. Double labeled: red - Reln; green - Cxcl12 (assay MGI:6281172).
Structure Level Pattern Image Note
TS23: cerebral cortex Present 3D , 3D'' Expression was in Cajal-Retzius cells, which were displaced in the mutant.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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03/25/2025
MGI 6.24 		The Jackson Laboratory