Summary | Transgene origin | Transgene description | Recombinase activity | Find Mice (IMSR) | References

Symbol:	Tg(Clec4g-icre)1.1Sgoe
Name:	transgene insertion 1.1, Sergij Goerdt
MGI ID:	MGI:6280453
Synonyms:	Clec4g-Cre, Tg(Clec4g-cre)1.1
Transgene:	Tg(Clec4g-icre)1.1Sgoe  Location: unknown
Alliance:	Tg(Clec4g-icre)1.1Sgoe page

Strain of Origin:

C57BL/6NCrl

Transgene Type:    Transgenic (Recombinase) Mutation:    Insertion   Tg(Clec4g-icre)1.1Sgoe expression driven by 1 gene Transgene expression driven by: Organism Driver Gene Note mouse Clec4g (MGI:1923113)   Mutation details: A cDNA containing a codon improved version of cre recombinase followed by polyA signal sequence was fused in frame into a BAC clone (RPCI-23-239-A7) at exon 1 of mouse Clec4g so that cre expression is driven by the regulatory sequences of the BAC gene. The resulting modified BAC was used to generate this transgene. Three founder lines 1.1, 1.2 and 1.3 were identified. (J:271085)

Activity:	Tissue activity of this recombinase allele
Driver:	Clec4g (mouse) Summary of all recombinase alleles driven by Clec4g. Alliance mouse Clec4g gene page

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 0 strains available      Cell Lines: 0 lines available

Original:	J:271085 Wohlfeil SA, et al., Hepatic Endothelial Notch Activation Protects against Liver Metastasis by Regulating Endothelial-Tumor Cell Adhesion Independent of Angiocrine Signaling. Cancer Res. 2019 Feb 1;79(3):598-610
All:	3 reference(s)