Tg(LCR-HBG2*/HBG1)100Hhb
Transgene Detail
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| Symbol: |
Tg(LCR-HBG2*/HBG1)100Hhb |
| Name: |
transgene insertion 100, Henny Billett |
| MGI ID: |
MGI:6277080 |
| Synonyms: |
gammaH |
| Transgene: |
Tg(LCR-HBG2*/HBG1)100Hhb Location: unknown
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| Alliance: |
Tg(LCR-HBG2*/HBG1)100Hhb page
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| Strain of Origin: |
Not Specified
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| Transgene Type: |
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Transgenic (Humanized sequence, Inserted expressed sequence) |
| Mutation: |
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Insertion
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Mutation details: The transgene contains a PCR-generated fragment of HS4 of the locus control region (LCR) of the human HBB gene region (951-2204) inserted into a 12.4-kb fragment of the human HBB gene region (32837-45203) including the mutant human HBG2 gene with a T at position -158 relative to the cap site, the HBG1 gene and the 3' enhancer. Founder line G100 was established.
(J:66961)
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| Mouse strains and cell lines
available from the International Mouse Strain Resource
(IMSR) |
| Carrying this Mutation: |
Mouse Strains: 1 strain available
Cell Lines: 0 lines available
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| Original: |
J:66961 Fabry ME, et al., Second generation knockout sickle mice: the effect of HbF. Blood. 2001 Jan 15;97(2):410-8 |
| All: |
2 reference(s) |
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Analysis Tools
