Gene Expression Data
Assay Details
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Assay
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Reference:
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J:116785
Kettunen P, et al., Histological development and dynamic expression of Bmp2-6 mRNAs in the embryonic and postnatal mouse cranial base. Anat Rec A Discov Mol Cell Evol Biol. 2006 Dec;288(12):1250-8
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Assay type:
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RNA in situ
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MGI Accession ID:
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MGI:6277113
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Gene symbol:
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Bmp2
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Gene name:
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bone morphogenetic protein 2
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Probe:
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Bmp2 probe16
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Probe preparation:
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Antisense labelled with S35 RNA
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Visualized with:
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Autoradiography
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Results
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Specimen
2A:
embryonic day 10.5
(more  )
Specimen
2A:
(close  )
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Genetic Background:
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NMRI
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Age:
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embryonic day 10.5
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Age Note:
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Age normalized so that noon of plug day = E0.5.
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Sex:
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Not Specified
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Type:
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section
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Fixation:
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4% Paraformaldehyde
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Embedding:
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Paraffin
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| Structure |
Level |
Pattern |
Image |
Note |
| TS17: craniocervical region |
Present |
Regionally restricted |
2A
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Expression is in the loose mesenchyme next to the foregut epithelium in the prospective cranial base area.
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| TS17: embryo mesenchyme |
Present |
Regionally restricted |
2A
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Expression is in the loose mesenchyme next to the foregut epithelium in the prospective cranial base area.
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Specimen
2B:
embryonic day 11.5
(more )
Specimen
2B:
(close )
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Genetic Background:
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NMRI
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Age:
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embryonic day 11.5
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Age Note:
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Age normalized so that noon of plug day = E0.5.
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Sex:
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Not Specified
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Type:
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section
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Fixation:
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4% Paraformaldehyde
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Embedding:
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Paraffin
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| Structure |
Level |
Pattern |
Image |
Note |
| TS19: craniocervical region |
Present |
Regionally restricted |
2B
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Expression is in the first mesenchymal condensations that mark the sites of the future basioccipital and basisphenoidal bones.
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| TS19: skeleton |
Present |
Regionally restricted |
2B
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Expression is in the first mesenchymal condensations that mark the sites of the future basioccipital and basisphenoidal bones.
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Specimen
2C:
embryonic day 12.5
(more )
Specimen
2C:
(close )
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Genetic Background:
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NMRI
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Age:
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embryonic day 12.5
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Age Note:
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Age normalized so that noon of plug day = E0.5.
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Sex:
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Not Specified
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Type:
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section
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Fixation:
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4% Paraformaldehyde
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Embedding:
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Paraffin
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| Structure |
Level |
Pattern |
Image |
Note |
| TS20: chondrocranium |
Present |
Regionally restricted |
2C
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Expression is at the anterior cranial base and was downregulated in the differentiating chondrocytes at the caudal end of the basioccipital cartilage but remained in the surrounding condensations.
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Specimen
2D:
embryonic day 13.5
(more )
Specimen
2D:
(close )
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Genetic Background:
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NMRI
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Age:
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embryonic day 13.5
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Age Note:
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Age normalized so that noon of plug day = E0.5.
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Sex:
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Not Specified
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Type:
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section
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Fixation:
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4% Paraformaldehyde
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Embedding:
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Paraffin
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| Structure |
Level |
Pattern |
Image |
Note |
| TS21: cranium |
Present |
Regionally restricted |
2D
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Expression is in the perichondrium of the cranial base.
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| TS21: perichondrium |
Present |
Regionally restricted |
2D
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Expression is in the perichondrium of the cranial base.
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Specimen
2E:
embryonic day 14.5
(more )
Specimen
2E:
(close )
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Genetic Background:
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NMRI
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Age:
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embryonic day 14.5
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Age Note:
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Age normalized so that noon of plug day = E0.5.
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Sex:
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Not Specified
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Type:
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section
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Fixation:
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4% Paraformaldehyde
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Embedding:
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Paraffin
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Specimen
2F:
embryonic day 16.5
(more )
Specimen
2F:
(close )
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Genetic Background:
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NMRI
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Age:
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embryonic day 16.5
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Age Note:
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Age normalized so that noon of plug day = E0.5.
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Sex:
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Not Specified
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Type:
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section
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Fixation:
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4% Paraformaldehyde
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Embedding:
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Paraffin
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| Structure |
Level |
Pattern |
Image |
Note |
| TS24: basioccipital bone |
Present |
Regionally restricted |
2F
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Expression is in hypertrophic chondrocytes in the spheno-occipital synchondrosis.
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| TS24: cranial synchondrosis |
Present |
Regionally restricted |
2F
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Expression is in hypertrophic chondrocytes in the spheno-occipital synchondrosis.
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| TS24: sphenoid bone |
Present |
Regionally restricted |
2F
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Expression is in hypertrophic chondrocytes in the spheno-occipital synchondrosis.
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| TS24: perichondrium |
Present |
Regionally restricted |
2F
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Expression is in the perichondrium next to the developing spheno-occipital synchondrosis.
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Specimen
2G:
postnatal newborn
(more )
Specimen
2G:
(close )
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Genetic Background:
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NMRI
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Age:
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postnatal newborn
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Sex:
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Not Specified
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Type:
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section
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Fixation:
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4% Paraformaldehyde
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Embedding:
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Paraffin
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| Structure |
Level |
Pattern |
Image |
Note |
| TS27: basioccipital bone |
Present |
Regionally restricted |
2G
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Expression is in hypertrophic chondrocytes in the spheno-occipital synchondrosis.
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| TS27: cranial synchondrosis |
Present |
Regionally restricted |
2G
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Expression is in hypertrophic chondrocytes in the spheno-occipital synchondrosis.
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| TS27: sphenoid bone |
Present |
Regionally restricted |
2G
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Expression is in hypertrophic chondrocytes in the spheno-occipital synchondrosis.
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| TS27: perichondrium |
Present |
Regionally restricted |
2G
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Expression is in the perichondrium next to the developing spheno-occipital synchondrosis.
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Specimen
2H:
postnatal day 5
(more )
Specimen
2H:
(close )
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Genetic Background:
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NMRI
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Age:
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postnatal day 5
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Sex:
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Not Specified
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Type:
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section
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Fixation:
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4% Paraformaldehyde
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Embedding:
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Paraffin
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| Structure |
Level |
Pattern |
Image |
Note |
| TS28: basioccipital bone |
Present |
Regionally restricted |
2H
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Expression is in hypertrophic chondrocytes in the spheno-occipital synchondrosis.
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| TS28: cranial synchondrosis |
Present |
Regionally restricted |
2H
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Expression is in hypertrophic chondrocytes in the spheno-occipital synchondrosis.
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| TS28: sphenoid bone |
Present |
Regionally restricted |
2H
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Expression is in hypertrophic chondrocytes in the spheno-occipital synchondrosis.
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| TS28: perichondrium |
Present |
Regionally restricted |
2H
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Expression is in the perichondrium next to the developing spheno-occipital synchondrosis.
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