About   Help   FAQ
Traf6tm2.1Ywc
Targeted Allele Detail
Summary
Symbol: Traf6tm2.1Ywc
Name: TNF receptor-associated factor 6; targeted mutation 2.1, Yongwon Choi
MGI ID: MGI:6275149
Synonyms: Traf6floxed
Gene: Traf6  Location: Chr2:101508774-101532014 bp, + strand  Genetic Position: Chr2, 53.9 cM
Alliance: Traf6tm2.1Ywc page
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:101977
Parent Cell Line:  Not Specified (ES Cell)
Strain of Origin:  Not Specified
Mutation
description
Allele Type:    Targeted (Conditional ready, No functional change)
Mutation:    Insertion
 
Mutation details: A floxed neomycin selection cassette was placed upstream of exon 7 and a STOP cassette followed by a loxP site and an YFP reporter were placed downstream of exon 7. Cre-mediated recombination removed the floxed neo cassette. (J:85808)
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Traf6 Mutation:  31 strains or lines available
Notes
The version of this allele that contains the neomycin selection cassette, Traf6tm2Ywc, has been analyzed.
References
Original:  J:85808 Kobayashi T, et al., TRAF6 is a critical factor for dendritic cell maturation and development. Immunity. 2003 Sep;19(3):353-63
All:  2 reference(s)
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support. 		last database update
04/16/2024
MGI 6.23 		The Jackson Laboratory