Tg(Thy1-MFN2*R94Q)44Balo
Transgene Detail
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| Symbol: |
Tg(Thy1-MFN2*R94Q)44Balo |
| Name: |
transgene insertion 44, Robert Balo |
| MGI ID: |
MGI:6274374 |
| Synonyms: |
MFN2R94Q |
| Transgene: |
Tg(Thy1-MFN2*R94Q)44Balo Location: unknown Genetic Position: ChrY, Syntenic
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| Alliance: |
Tg(Thy1-MFN2*R94Q)44Balo page
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| Transgene Type: |
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Transgenic (Humanized sequence, Inserted expressed sequence) |
| Mutations: |
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Insertion, Nucleotide substitutions
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Tg(Thy1-MFN2*R94Q)44Balo expresses
1 gene
Transgene expresses:
| Organism |
Expressed Gene |
Homolog in Mouse |
Note |
| human |
MFN2 (9927) |
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flag tagged human cDNA with R94Q mutation |
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Mutation details: The 9102 bp transgenic construct contains a murine thymus cell antigen 1, theta (Thy1) promoter driving expression of a flag-tagged human mitofusin 2 (MFN2) gene containing an R94Q mutation.
(J:273854)
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| Mouse strains and cell lines
available from the International Mouse Strain Resource
(IMSR) |
| Carrying this Mutation: |
Mouse Strains: 1 strain available
Cell Lines: 0 lines available
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| Original: |
J:273854 Zhou Y, et al., Restoring mitofusin balance prevents axonal degeneration in a Charcot-Marie-Tooth type 2A model. J Clin Invest. 2019 Mar 18;130:1756-1771 |
| All: |
2 reference(s) |
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Analysis Tools
