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Tg(Myh6-ALDH2)1Doc
Transgene Detail
Summary
Symbol: Tg(Myh6-ALDH2)1Doc
Name: transgene insertion 1, Bradford Hill
MGI ID: MGI:6273995
Synonyms: ALDH2 Tg
Transgene: Tg(Myh6-ALDH2)1Doc  Location: unknown  
Alliance: Tg(Myh6-ALDH2)1Doc page
Transgene
origin
Strain of Origin:  C57BL/6
Transgene
description
Transgene Type:    Transgenic (Humanized sequence, Inserted expressed sequence)
Mutation:    Insertion
 
Tg(Myh6-ALDH2)1Doc expresses 1 gene
 
Mutation detailsThe transgenic construct contains a mouse alpha myosin heavy chain (alpha-MHC or Myh6) promoter directing expression of the human ALDH2 cDNA (1.58 Kb) followed by a human growth hormone (hGH) gene containing a polyA signal. (J:267244)
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
References
Original:  J:267244 Dassanayaka S, et al., Cardiac-specific overexpression of aldehyde dehydrogenase 2 exacerbates cardiac remodeling in response to pressure overload. Redox Biol. 2018 Jul;17:440-449
All:  1 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
03/25/2025
MGI 6.24
The Jackson Laboratory