Tg(Myh6-ALDH2)1Doc
Transgene Detail
|
Symbol: |
Tg(Myh6-ALDH2)1Doc |
Name: |
transgene insertion 1, Bradford Hill |
MGI ID: |
MGI:6273995 |
Synonyms: |
ALDH2 Tg |
Transgene: |
Tg(Myh6-ALDH2)1Doc Location: unknown
|
Alliance: |
Tg(Myh6-ALDH2)1Doc page
|
|
|
Transgene Type: |
|
Transgenic (Humanized sequence, Inserted expressed sequence) |
Mutation: |
|
Insertion
|
|
|
Tg(Myh6-ALDH2)1Doc expresses
1 gene
Transgene expresses:
Organism |
Expressed Gene |
Homolog in Mouse |
Note |
human |
ALDH2 (217) |
|
|
|
|
|
Mutation details: The transgenic construct contains a mouse alpha myosin heavy chain (alpha-MHC or Myh6) promoter directing expression of the human ALDH2 cDNA (1.58 Kb) followed by a human growth hormone (hGH) gene containing a polyA signal.
(J:267244)
|
|
|
Mouse strains and cell lines
available from the International Mouse Strain Resource
(IMSR) |
Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available
|
|
Original: |
J:267244 Dassanayaka S, et al., Cardiac-specific overexpression of aldehyde dehydrogenase 2 exacerbates cardiac remodeling in response to pressure overload. Redox Biol. 2018 Jul;17:440-449 |
All: |
1 reference(s) |
|