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Gene Expression Data
Assay Details
Assay
Reference: J:64679 Zheng JL, et al., Hes1 is a negative regulator of inner ear hair cell differentiation. Development. 2000 Nov;127(21):4551-60
Assay type: Immunohistochemistry
MGI Accession ID: MGI:6272365
Gene symbol: Myo7a
Gene name: myosin VIIA
Results
Specimen 1D: embryonic day 17.5 (more )
Structure Level Pattern Image Note
TS25: cochlea epithelium Present Regionally restricted 1D Expression is in hair cells.

Specimen 1E: embryonic day 17.5; Hes1tm1Fgu/Hes1+ (more )
Structure Level Pattern Image Note
TS25: cochlea epithelium Present Regionally restricted 1E Expression is in hair cells. Heterozygotes had a small increase in the number of inner hair cells.

Specimen 1F: embryonic day 17.5; Hes1tm1Fgu/Hes1tm1Fgu (more )
Structure Level Pattern Image Note
TS25: cochlea epithelium Present Regionally restricted 1F Expression is in hair cells. This mutant has supernumerary inner hair cells compared to +/+.

Specimen 4A: embryonic day 17.5 (more )
Structure Level Pattern Image Note
TS25: utricle Present Regionally restricted 4A Expression is in hair cells.

Specimen 4B: embryonic day 17.5; Hes1tm1Fgu/Hes1tm1Fgu (more )
Structure Level Pattern Image Note
TS25: utricle Present Regionally restricted 4B Expression is in hair cells. This mutant has supernumerary hair cells compared to +/+.

Specimen not shown +/-: embryonic day 17.5; Hes1tm1Fgu/Hes1+ (more )
Structure Level Pattern Image Note
TS25: utricle Present Regionally restricted Expression is in hair cells. Heterozygotes had a small increase in the number of hair cells.


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
03/25/2025
MGI 6.24
The Jackson Laboratory