Gene Expression Data
Assay Details
Assay
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Reference:
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J:64679
Zheng JL, et al., Hes1 is a negative regulator of inner ear hair cell differentiation. Development. 2000 Nov;127(21):4551-60
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Assay type:
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Immunohistochemistry
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MGI Accession ID:
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MGI:6272365
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Gene symbol:
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Myo7a
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Gene name:
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myosin VIIA
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Results
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Specimen
1D:
embryonic day 17.5
(more )
Specimen
1D:
(close )
Genetic Background:
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involves: 129S1/Sv * 129X1/SvJ * CD-1
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Age:
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embryonic day 17.5
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Sex:
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Not Specified
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Type:
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section
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Fixation:
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4% Paraformaldehyde
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Embedding:
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Cryosection
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Specimen
1E:
embryonic day 17.5; Hes1tm1Fgu/Hes1 +
(more )
Specimen
1E:
(close )
Genetic Background:
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involves: 129S1/Sv * 129X1/SvJ * CD-1
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Mutant Allele(s):
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Hes1tm1Fgu/Hes1+
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Age:
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embryonic day 17.5
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Sex:
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Not Specified
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Type:
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section
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Fixation:
|
4% Paraformaldehyde
|
Embedding:
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Cryosection
|
Structure |
Level |
Pattern |
Image |
Note |
TS25: cochlea epithelium |
Present |
Regionally restricted |
1E
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Expression is in hair cells. Heterozygotes had a small increase in the number of inner hair cells.
|
Specimen
1F:
(close )
Genetic Background:
|
involves: 129S1/Sv * 129X1/SvJ * CD-1
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Mutant Allele(s):
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Hes1tm1Fgu/Hes1tm1Fgu
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Age:
|
embryonic day 17.5
|
Sex:
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Not Specified
|
Type:
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section
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Fixation:
|
4% Paraformaldehyde
|
Embedding:
|
Cryosection
|
Structure |
Level |
Pattern |
Image |
Note |
TS25: cochlea epithelium |
Present |
Regionally restricted |
1F
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Expression is in hair cells. This mutant has supernumerary inner hair cells compared to +/+.
|
Specimen
4A:
embryonic day 17.5
(more )
Specimen
4A:
(close )
Genetic Background:
|
involves: 129S1/Sv * 129X1/SvJ * CD-1
|
Age:
|
embryonic day 17.5
|
Sex:
|
Not Specified
|
Type:
|
section
|
Fixation:
|
4% Paraformaldehyde
|
Embedding:
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Cryosection
|
Structure |
Level |
Pattern |
Image |
Note |
TS25: utricle |
Present |
Regionally restricted |
4A
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Expression is in hair cells.
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Specimen
4B:
(close )
Genetic Background:
|
involves: 129S1/Sv * 129X1/SvJ * CD-1
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Mutant Allele(s):
|
Hes1tm1Fgu/Hes1tm1Fgu
|
Age:
|
embryonic day 17.5
|
Sex:
|
Not Specified
|
Type:
|
section
|
Fixation:
|
4% Paraformaldehyde
|
Embedding:
|
Cryosection
|
Structure |
Level |
Pattern |
Image |
Note |
TS25: utricle |
Present |
Regionally restricted |
4B
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Expression is in hair cells. This mutant has supernumerary hair cells compared to +/+.
|
Specimen
not shown +/-:
embryonic day 17.5; Hes1tm1Fgu/Hes1 +
(more )
Specimen
not shown +/-:
(close )
Genetic Background:
|
involves: 129S1/Sv * 129X1/SvJ * CD-1
|
Mutant Allele(s):
|
Hes1tm1Fgu/Hes1+
|
Age:
|
embryonic day 17.5
|
Sex:
|
Not Specified
|
Type:
|
section
|
Fixation:
|
4% Paraformaldehyde
|
Embedding:
|
Cryosection
|
Structure |
Level |
Pattern |
Image |
Note |
TS25: utricle |
Present |
Regionally restricted |
|
Expression is in hair cells. Heterozygotes had a small increase in the number of hair cells.
|
|