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Gene Expression Data
Assay Details
Assay
Reference: J:31372 Tanaka Y, et al., Messenger RNA expression of heat shock proteins (HSPs) during ocular development. Curr Eye Res. 1995 Dec;14(12):1125-33
Assay type: RNA in situ
MGI Accession ID: MGI:6272285
Gene symbol: Hsp90aa1
Gene name: heat shock protein 90, alpha (cytosolic), class A member 1
Probe: HSP86 cDNA2
Probe preparation: Antisense labelled with digoxigenin RNA
Results
Specimen 4A: embryonic day 12.5 (more )
Structure Level Pattern Image Note
TS20: eye Present 4A Expression was detected in all ocular tissues.

Specimen 4B: embryonic day 13.5 (more )
Structure Level Pattern Image Note
TS21: lens epithelium Strong 4B
TS21: neural retina Strong 4B

Specimen 4C: embryonic day 14.5 (more )
Structure Level Pattern Image Note
TS22: lens epithelium Strong 4C
TS22: neural retina Strong 4C

Specimen 4D: embryonic day 16.5 (more )
Structure Level Pattern Image Note
TS24: eye Weak Regionally restricted 4D Expression levels decreased at stage 6 in ocular tissues, especially the cornea, but remained in the lid, equator of the lens epithelium and intensive expression in the neuroectoderm.
TS24: cornea Absent 4D
TS24: eyelid Present 4D
TS24: neural retina Strong 4D
TS24: lens epithelium Present Regionally restricted 4D Expression was detected in the equator of the lens epithelium.

Specimen 4E: embryonic day 18.5 (more )
Structure Level Pattern Image Note
TS26: eye Present Regionally restricted 4E Expression was decreased in all ocular tissues except for the retina.
TS26: retina Present 4E

Specimen 6C: embryonic day 18.5 (more )
Structure Level Pattern Image Note
TS26: retina layer Present Regionally restricted 6C Expression was in the neuroblastic cell layer and ganglion cells.
TS26: retina ganglion cell layer Present 6C

Specimen 7C: postnatal day 50 (more )
Structure Level Pattern Image Note
TS28: photoreceptor layer inner segment Present 7C
TS28: retina ganglion cell layer Present 7C
TS28: retina inner nuclear layer Present 7C

Specimen Table 2 stage 3: embryonic day 12.5 (more )
Structure Level Pattern Image Note
TS20: eye Strong Regionally restricted Expression was strong in cornea, lens, neuroectoderm, choroid, sclera, lid, and conjunctiva.
TS20: cornea Strong
TS20: lens vesicle Strong
TS20: neural retina Strong

Specimen Table 2 stage 4: embryonic day 13.5 (more )
Structure Level Pattern Image Note
TS21: eye Strong Regionally restricted Expression was strong in cornea, lens, neuroectoderm, choroid, sclera, lid, and conjunctiva.
TS21: choroidal vasculature Strong
TS21: cornea Strong
TS21: eyelid Strong
TS21: lens Strong
TS21: neural retina Strong

Specimen Table 2 stage 5: embryonic day 14.5 (more )
Structure Level Pattern Image Note
TS22: eye Strong Regionally restricted Expression was strong in cornea, lens, neuroectoderm, choroid, sclera, lid, and conjunctiva.
TS22: choroidal vasculature Strong
TS22: conjunctival sac Strong
TS22: cornea Strong
TS22: eyelid Strong
TS22: lens Strong
TS22: neural retina Strong

Specimen Table 2 stage 6: embryonic day 16.5 (more )
Structure Level Pattern Image Note
TS24: choroidal vasculature Present
TS24: conjunctival sac Present
TS24: eyelid Present
TS24: lens Present
TS24: sclera Present
TS24: cornea Absent
TS24: neural retina Strong

Specimen Table 2 stage 7: embryonic day 18.5 (more )
Structure Level Pattern Image Note
TS26: choroidal vasculature Absent
TS26: conjunctival sac Absent
TS26: cornea Absent
TS26: eyelid Absent
TS26: lens Absent
TS26: sclera Absent
TS26: neural retina Strong

Specimen Table 2 postnatal 50-day-old: postnatal day 50 (more )
Structure Level Pattern Image Note
TS28: choroidal vasculature Absent
TS28: conjunctival sac Absent
TS28: cornea Absent
TS28: eyelid Absent
TS28: lens Absent
TS28: sclera Absent
TS28: neural retina Strong


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/30/2024
MGI 6.23
The Jackson Laboratory