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Gene Expression Data
Assay Details
Assay
Reference: J:31372 Tanaka Y, et al., Messenger RNA expression of heat shock proteins (HSPs) during ocular development. Curr Eye Res. 1995 Dec;14(12):1125-33
Assay type: RNA in situ
MGI Accession ID: MGI:6272277
Gene symbol: Hsp90ab1
Gene name: heat shock protein 90 alpha (cytosolic), class B member 1
Probe: HSP84 cDNA2
Probe preparation: Antisense labelled with digoxigenin RNA
Results
Specimen 3A: embryonic day 12.5 (more )
Structure Level Pattern Image Note
TS20: eye Present Regionally restricted 3A Expression was detected in all ocular tissues: the developing cornea, lens, neuroectoderm, choroid, sclera, and lid. Especially strong labeling was seen in the lens epithelium, neuroectoderm, surface ectoderm of the presumptive lid and conjunctiva.
TS20: cornea Present 3A
TS20: lens vesicle Strong 3A
TS20: neural retina Strong 3A

Specimen 3B: embryonic day 13.5 (more )
Structure Level Pattern Image Note
TS21: eye Present Regionally restricted 3B Expression was detected in all ocular tissues: the developing cornea, lens, neuroectoderm, choroid, sclera, and lid. Especially strong labeling was seen in the lens epithelium, neuroectoderm, surface ectoderm of the presumptive lid and conjunctiva.
TS21: choroidal vasculature Present 3B
TS21: cornea Present 3B
TS21: eyelid Strong 3B
TS21: lens epithelium Strong 3B
TS21: neural retina Strong 3B

Specimen 3C: embryonic day 14.5 (more )
Structure Level Pattern Image Note
TS22: eye Present Regionally restricted 3C Expression was detected in all ocular tissues: the developing cornea, lens, neuroectoderm, choroid, sclera, and lid. Especially strong labeling was seen in the lens epithelium, neuroectoderm, surface ectoderm of the presumptive lid and conjunctiva.
TS22: choroidal vasculature Present 3C
TS22: cornea Present 3C
TS22: conjunctival sac Strong 3C
TS22: eyelid Strong 3C
TS22: lens epithelium Strong 3C
TS22: neural retina Strong 3C

Specimen 3D: embryonic day 16.5 (more )
Structure Level Pattern Image Note
TS24: eye Weak Regionally restricted 3D At stage 6 (E15.5-16.5), expression was much weaker in all ocular tissues.
TS24: cornea Absent 3D
TS24: conjunctival sac Present 3D
TS24: eyelid Present 3D
TS24: lens epithelium Present Regionally restricted 3D Expression was detected at the equator of the lens epithelium.

Specimen 3E: embryonic day 18.5 (more )
Structure Level Pattern Image Note
TS26: eye Absent 3E

Specimen 6B: embryonic day 18.5 (more )
Structure Level Pattern Image Note
TS26: retina layer Weak Regionally restricted 6B Weakly labeled cells were observed in the neuroblastic cell layer, ganglion cells, and retinal pigment epithelium.
TS26: pigmented retinal epithelium Weak 6B

Specimen 7B: postnatal day 50 (more )
Structure Level Pattern Image Note
TS28: retina Absent 7B

Specimen Table 2 stage 3: embryonic day 12.5 (more )
Structure Level Pattern Image Note
TS20: eye Strong Regionally restricted Expression was strong in cornea, lens, neuroectoderm, choroid, sclera, lid, and conjunctiva.
TS20: cornea Strong
TS20: lens vesicle Strong
TS20: neural retina Strong

Specimen Table 2 stage 4: embryonic day 13.5 (more )
Structure Level Pattern Image Note
TS21: eye Strong Regionally restricted Expression was strong in cornea, lens, neuroectoderm, choroid, sclera, lid, and conjunctiva.
TS21: choroidal vasculature Strong
TS21: cornea Strong
TS21: eyelid Strong
TS21: lens Strong
TS21: neural retina Strong

Specimen Table 2 stage 5: embryonic day 14.5 (more )
Structure Level Pattern Image Note
TS22: eye Strong Regionally restricted Expression was strong in cornea, lens, neuroectoderm, choroid, sclera, lid, and conjunctiva.
TS22: choroidal vasculature Strong
TS22: conjunctival sac Strong
TS22: cornea Strong
TS22: eyelid Strong
TS22: lens Strong
TS22: neural retina Strong

Specimen Table 2 stage 6: embryonic day 16.5 (more )
Structure Level Pattern Image Note
TS24: cornea Absent
TS24: choroidal vasculature Present
TS24: conjunctival sac Present
TS24: eyelid Present
TS24: lens Present
TS24: sclera Present
TS24: neural retina Strong

Specimen Table 2 stage 7: embryonic day 18.5 (more )
Structure Level Pattern Image Note
TS26: choroidal vasculature Absent
TS26: conjunctival sac Absent
TS26: cornea Absent
TS26: eyelid Absent
TS26: lens Absent
TS26: sclera Absent
TS26: neural retina Present

Specimen Table 2 Postnatal 50-day-old: postnatal day 50 (more )
Structure Level Pattern Image Note
TS28: choroidal vasculature Absent
TS28: conjunctival sac Absent
TS28: cornea Absent
TS28: eyelid Absent
TS28: lens Absent
TS28: neural retina Absent
TS28: sclera Absent


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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
05/21/2024
MGI 6.23
The Jackson Laboratory