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Gene Expression Data
Assay Details
Assay
Reference: J:31372 Tanaka Y, et al., Messenger RNA expression of heat shock proteins (HSPs) during ocular development. Curr Eye Res. 1995 Dec;14(12):1125-33
Assay type: RNA in situ
MGI Accession ID: MGI:6272263
Gene symbol: Hspa8
Gene name: heat shock protein 8
Probe: HSC70 cDNA4
Probe preparation: Antisense labelled with digoxigenin RNA
Results
Specimen 2A: embryonic day 12.5 (more )
Structure Level Pattern Image Note
TS20: eye Strong Regionally restricted 2A Expression was strong in all ocular tissues: the developing cornea, lens, neuroectoderm, choroid, sclera, lid and conjunctiva.
TS20: cornea Strong 2A
TS20: lens vesicle Strong 2A
TS20: neural retina Strong 2A

Specimen 2B: embryonic day 13.5 (more )
Structure Level Pattern Image Note
TS21: eye Strong Regionally restricted 2B Expression was strong in all ocular tissues: the developing cornea, lens, neuroectoderm, choroid, sclera, lid and conjunctiva.
TS21: choroidal vasculature Strong 2B
TS21: cornea Strong 2B
TS21: eyelid Strong 2B
TS21: lens Strong 2B
TS21: neural retina Strong 2B

Specimen 2C: embryonic day 14.5 (more )
Structure Level Pattern Image Note
TS22: eye Strong Regionally restricted 2C Expression was strong in all ocular tissues: the developing cornea, lens, neuroectoderm, choroid, sclera, lid and conjunctiva.
TS22: choroidal vasculature Strong
TS22: conjunctival sac Strong
TS22: cornea Strong
TS22: eyelid Strong
TS22: lens Strong
TS22: neural retina Strong

Specimen 2D: embryonic day 16.5 (more )
Structure Level Pattern Image Note
TS24: eye Strong Regionally restricted 2D At stage 6 (E15.5-16.5), expression was decreased in the cornea, choroid and sclera, but was still high in the equator of the lens epithelium, lid, conjunctiva, and retina.
TS24: conjunctival sac Strong 2D
TS24: eyelid Strong 2D
TS24: retina Strong 2D
TS24: lens epithelium Strong Regionally restricted 2D Expression was strong in the equator of the lens epithelium.

Specimen 2E: embryonic day 18.5 (more )
Structure Level Pattern Image Note
TS26: conjunctival sac Weak 2E
TS26: eyelid Weak 2E
TS26: lens epithelium Weak 2E
TS26: retina Present 2E

Specimen 6A: embryonic day 18.5 (more )
Structure Level Pattern Image Note
TS26: retina layer Strong Regionally restricted 6A Expression was strong in the neuroblastic layer and ganglion cells.

Specimen 7A: postnatal day 50 (more )
Structure Level Pattern Image Note
TS28: photoreceptor layer inner segment Present 7A
TS28: retina ganglion cell layer Present 7A
TS28: retina inner nuclear layer Present 7A

Specimen Table 2 stage 3: embryonic day 12.5 (more )
Structure Level Pattern Image Note
TS20: eye Strong Regionally restricted Expression was strong in cornea, lens, neuroectoderm, choroid, sclera, lid, and conjunctiva.
TS20: cornea Strong
TS20: lens vesicle Strong
TS20: neural retina Strong

Specimen Table 2 stage 4: embryonic day 13.5 (more )
Structure Level Pattern Image Note
TS21: eye Strong Regionally restricted Expression was strong in cornea, lens, neuroectoderm, choroid, sclera, lid, and conjunctiva.
TS21: choroidal vasculature Strong
TS21: cornea Strong
TS21: eyelid Strong
TS21: lens Strong
TS21: neural retina Strong

Specimen Table 2 stage 5: embryonic day 14.5 (more )
Structure Level Pattern Image Note
TS22: eye Strong Regionally restricted Expression was strong in cornea, lens, neuroectoderm, choroid, sclera, lid, and conjunctiva.
TS22: choroidal vasculature Strong
TS22: conjunctival sac Strong
TS22: cornea Strong
TS22: eyelid Strong
TS22: lens Strong
TS22: neural retina Strong

Specimen Table 2 stage 6: embryonic day 16.5 (more )
Structure Level Pattern Image Note
TS24: choroidal vasculature Present
TS24: cornea Present
TS24: sclera Present
TS24: conjunctival sac Strong
TS24: eyelid Strong
TS24: lens Strong
TS24: neural retina Strong

Specimen Table 2 stage 7: embryonic day 18.5 (more )
Structure Level Pattern Image Note
TS26: choroidal vasculature Absent
TS26: cornea Absent
TS26: sclera Absent
TS26: conjunctival sac Present
TS26: eyelid Present
TS26: lens Present
TS26: neural retina Strong

Specimen Table 2 Postnatal 50-day-old: postnatal day 50 (more )
Structure Level Pattern Image Note
TS28: neural retina Strong
TS28: choroidal vasculature Absent
TS28: conjunctival sac Absent
TS28: cornea Absent
TS28: eyelid Absent
TS28: lens Absent
TS28: sclera Absent


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
05/21/2024
MGI 6.23
The Jackson Laboratory