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Tg(Cdkn1a*/tdTomato)260Rein
Transgene Detail
Summary
Symbol: Tg(Cdkn1a*/tdTomato)260Rein
Name: transgene insertion 260, H Christian Reinhardt
MGI ID: MGI:6270403
Synonyms: Cdkn1aLSL.SUPER
Transgene: Tg(Cdkn1a*/tdTomato)260Rein  Location: unknown  
Alliance: Tg(Cdkn1a*/tdTomato)260Rein page
Transgene
origin
Strain of Origin:  C57BL/6N
Transgene
description
Transgene Type:    Transgenic (Conditional ready, Inserted expressed sequence, Reporter)
Mutation:    Insertion
 
Tg(Cdkn1a*/tdTomato)260Rein expresses 1 gene
 
Mutation detailsBAC BMQ-448E21 carrying the genomic Cdkn1a mouse sequence was modified to replace the stop codon in exon 3 with a tdTomato reporter followed by polyA sequence. A loxP-STOP-loxP (LSL) cassette was inserted into intron 2. The transgene inserted on the centromeric region of chromosome 6. (J:266858)
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 0 lines available
References
Original:  J:266858 Torgovnick A, et al., The Cdkn1a(SUPER) Mouse as a Tool to Study p53-Mediated Tumor Suppression. Cell Rep. 2018 Oct 23;25(4):1027-1039.e6
All:  1 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
03/25/2025
MGI 6.24
The Jackson Laboratory