About   Help   FAQ
Gene Expression Data
Assay Details
Assay
Reference: J:266915 Bonet F, et al., CCBE1 is required for coronary vessel development and proper coronary artery stem formation in the mouse heart. Dev Dyn. 2018 Oct;247(10):1135-1145
Assay type: In situ reporter (knock in)
MGI Accession ID: MGI:6270175
Gene symbol: Ccbe1
Gene name: collagen and calcium binding EGF domains 1
Reporter: lacZ
Direct Detection
Results
Specimen 1A: embryonic day 11.5; Ccbe1tm1Lex/Ccbe1+ (more )
Structure Level Pattern Image Note
TS19: parietal pericardium Strong 1A

Specimen 1B/b'/b": embryonic day 11.5; Ccbe1tm1Lex/Ccbe1+ (more )
Structure Level Pattern Image Note
TS19: visceral pericardium Strong 1B , 1b'
TS19: sinus venosus Present Regionally restricted 1b" , 1B Expressed in myocardium.

Specimen 1C: embryonic day 12.5; Ccbe1tm1Lex/Ccbe1+ (more )
Structure Level Pattern Image Note
TS20: parietal pericardium Strong 1C

Specimen 1D/d'/d": embryonic day 12.5; Ccbe1tm1Lex/Ccbe1+ (more )
Structure Level Pattern Image Note
TS20: parietal pericardium Strong 1D , 1d'
TS20: visceral pericardium Strong 1D , 1d'
TS20: sinus venosus Present Regionally restricted 1D , 1d" Expressed in myocardium.

Specimen 1E: embryonic day 13.5; Ccbe1tm1Lex/Ccbe1+ (more )
Structure Level Pattern Image Note
TS21: parietal pericardium Present 1E

Specimen 1F/f'/f": embryonic day 13.5; Ccbe1tm1Lex/Ccbe1+ (more )
Structure Level Pattern Image Note
TS21: visceral pericardium Strong 1f' , 1F
TS21: heart blood vessel Present Regionally restricted 1F , 1f" Expressed in the sinus venosus epicardial layer.

Specimen 5D: embryonic day 13.5; Ccbe1tm1Lex/Ccbe1+ (more )
Structure Level Pattern Image Note
TS21: ascending aorta Present Regionally restricted 5D Expressed in the aortic epicardium.

Specimen not shown: embryonic day 11.5; Ccbe1tm1Lex/Ccbe1tm1Lex (more )
Structure Level Pattern Image Note
TS19: parietal pericardium Present Similar expression profile as in the heterozygous.
TS19: sinus venosus Present Similar expression profile as in the heterozygous.
TS19: visceral pericardium Present Similar expression profile as in the heterozygous.

Specimen not shown: embryonic day 12.5; Ccbe1tm1Lex/Ccbe1tm1Lex (more )
Structure Level Pattern Image Note
TS20: parietal pericardium Present Similar expression profile as in the heterozygous.
TS20: sinus venosus Present Similar expression profile as in the heterozygous.
TS20: visceral pericardium Present Similar expression profile as in the heterozygous.

Specimen not shown: embryonic day 13.5; Ccbe1tm1Lex/Ccbe1tm1Lex (more )
Structure Level Pattern Image Note
TS21: parietal pericardium Present Similar expression profile as in the heterozygous.
TS21: visceral pericardium Present Similar expression profile as in the heterozygous.
TS21: heart blood vessel Present Regionally restricted Similar expression profile as in the heterozygous in the sinus venosus epicardial layer.


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support.
last database update
05/14/2024
MGI 6.23
The Jackson Laboratory