Tg(CAG-GCH1)#Wlf
Transgene Detail
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| Symbol: |
Tg(CAG-GCH1)#Wlf |
| Name: |
transgene insertion, Clifford J Woolf |
| MGI ID: |
MGI:6269989 |
| Synonyms: |
GCH1-HA |
| Transgene: |
Tg(CAG-GCH1)#Wlf Location: unknown
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| Alliance: |
Tg(CAG-GCH1)#Wlf page
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| Strain of Origin: |
Not Specified
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| Transgene Type: |
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Transgenic (Conditional ready, Epitope tag, Humanized sequence, Inserted expressed sequence) |
| Mutation: |
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Insertion
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Tg(CAG-GCH1)#Wlf expresses
1 gene
Transgene expresses:
| Organism |
Expressed Gene |
Homolog in Mouse |
Note |
| human |
GCH1 (2643) |
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human cDNA with HA tag |
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Mutation details: The transgene contains the following elements: the CAG promoter, a loxP site, a neomycin resistance gene (including stop codon and poly(A) signal) a second loxP site, the human GCH1 cDNA with HA tag sequence coupled to it, and poly(A) signal sequence. This creates a conditional-ready allele that will express HA-tagged human GCH1 only after cre-mediated removal of the neo cassette.
(J:223362)
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| Mouse strains and cell lines
available from the International Mouse Strain Resource
(IMSR) |
| Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available
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| Original: |
J:223362 Latremoliere A, et al., Reduction of Neuropathic and Inflammatory Pain through Inhibition of the Tetrahydrobiopterin Pathway. Neuron. 2015 Jun 17;86(6):1393-406 |
| All: |
5 reference(s) |
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Analysis Tools
