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Gene Expression Data
Assay Details
Assay
Reference: J:163483 He G, et al., Inactivation of Six2 in mouse identifies a novel genetic mechanism controlling development and growth of the cranial base. Dev Biol. 2010 Aug 15;344(2):720-30
Assay type: RNA in situ
MGI Accession ID: MGI:6268343
Gene symbol: H4c3
Gene name: H4 clustered histone 3
Probe: H4C cDNA1
Probe preparation: Antisense RNA
Results
Specimen 4C: embryonic day 13.5 (more )
Structure Level Pattern Image Note
TS21: chondrocranium pre-cartilage condensation Present Regionally restricted 4C Expression in presphenoid bone chondrogenic condensation.
Specimen 4D: embryonic day 13.5; Six2tm1Gco/Six2tm1Gco (more )
Structure Level Pattern Image Note
TS21: chondrocranium pre-cartilage condensation Present Regionally restricted 4D No significant difference between wild-type and mutant presphenoid chondrogenic condensations.
Specimen 4G: embryonic day 14.5 (more )
Structure Level Pattern Image Note
TS22: chondrocranium cartilage condensation Present Regionally restricted 4G Expression in presphenoid bone precursor.
Specimen 4H: embryonic day 14.5; Six2tm1Gco/Six2tm1Gco (more )
Structure Level Pattern Image Note
TS22: chondrocranium cartilage condensation Weak Regionally restricted 4H Significant reduction in expressing cells in mutant presphenoid precursor compared to wild-type.
Specimen 4O: embryonic day 15.5 (more )
Structure Level Pattern Image Note
TS23: chondrocranium cartilage condensation Present Regionally restricted 4O
Specimen 4P: embryonic day 15.5; Six2tm1Gco/Six2tm1Gco (more )
Structure Level Pattern Image Note
TS23: chondrocranium cartilage condensation Present Regionally restricted 4P Expression in anterior one-third of presphenoid bone precursor.
Specimen 5C: embryonic day 14.5 (more )
Structure Level Pattern Image Note
TS22: chondrocranium cartilage condensation Present Regionally restricted 5C Expression in mid-posterior region of presphenoid bone precursor.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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04/30/2024
MGI 6.23 		The Jackson Laboratory