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Gene Expression Data
Assay Details
Assay
Reference: J:265810 Cabaud O, et al., Mutation of FOP/FGFR1OP in mice recapitulates human short rib-polydactyly ciliopathy. Hum Mol Genet. 2018 Oct 1;27(19):3377-3391
Assay type: Immunohistochemistry
MGI Accession ID: MGI:6259761
Gene symbol: Cep43
Gene name: centrosomal protein 43
Antibody: FGFR1OP Antibody
Detection system: Secondary antibody coupled to Cy3
Results
Specimen 3A lower left: embryonic day 17.5 (more )
Note: Double labeled: red - Cep43 (Fgfr1op); green - acetylated tubulin.
Structure Level Pattern Image Note
TS25: renal tubule Present Regionally restricted 3A lower left Expressed in the cilia.
Specimen 3A lower right: embryonic day 17.5; Cep43Gt(AX0127)Wtsi/Cep43Gt(AX0127)Wtsi (more )
Note: Double labeled: red - Cep43 (Fgfr1op); green - acetylated tubulin.
Structure Level Pattern Image Note
TS25: renal tubule Present Regionally restricted 3A lower right Expressed in the cilia, which were absent in most renal tubules.
Specimen 3B lower left: embryonic day 17.5 (more )
Note: Double labeled: red - Cep43 (Fgfr1op); green - acetylated tubulin.
Structure Level Pattern Image Note
TS25: lung Present 3B lower left
Specimen 3B lower right: embryonic day 17.5; Cep43Gt(AX0127)Wtsi/Cep43Gt(AX0127)Wtsi (more )
Note: Double labeled: red - Cep43 (Fgfr1op); green - acetylated tubulin.
Structure Level Pattern Image Note
TS25: lung Present 3B lower right A reduction of multiciliated cells in the airway epithelium was seen.
Specimen 3C left: embryonic day 16.5 (more )
Note: Double labeled: red - Cep43 (Fgfr1op); green - acetylated tubulin.
Structure Level Pattern Image Note
TS24: vibrissa follicle Present Regionally restricted 3C left Expressed in the primary cilia.
Specimen 3C right: embryonic day 16.5; Cep43Gt(AX0127)Wtsi/Cep43Gt(AX0127)Wtsi (more )
Note: Double labeled: red - Cep43 (Fgfr1op); green - acetylated tubulin.
Structure Level Pattern Image Note
TS24: vibrissa follicle Present Regionally restricted 3C right Expressed in the primary cilia.
Specimen not shown: embryonic day 16.5 (more )
Structure Level Pattern Image Note
TS24: vibrissa follicle Present Regionally restricted Expressed in the primary cilia.
Specimen not shown: embryonic day 15.5; Cep43Gt(AX0127)Wtsi/Cep43Gt(AX0127)Wtsi (more )
Structure Level Pattern Image Note
TS23: vibrissa follicle Present Regionally restricted Expressed in the primary cilia.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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04/23/2024
MGI 6.23 		The Jackson Laboratory