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Usp29tm2Jkim
Targeted Allele Detail
Summary
Symbol: Usp29tm2Jkim
Name: ubiquitin specific peptidase 29; targeted mutation 2, Joomyeong Kim
MGI ID: MGI:6258929
Gene: Usp29  Location: Chr7:6733577-6970218 bp, + strand  Genetic Position: Chr7, 4.04 cM
Alliance: Usp29tm2Jkim page
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:245745
Parent Cell Line:  AB2.2 (ES Cell)
Strain of Origin:  129S7/SvEvBrd-Hprt1b-m2
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutation:    Insertion
 
Mutation detailsA loxP site and an FRT site flanked neomycin resistance gene cassette (in the same transcriptional direction as the targeted gene) were inserted into intron 1. A second loxP site was inserted into intron 1 of upstream neighbor Peg3 (with which it shares a bidirectional promoter), in the opposite orientation of the first loxP site, upstream of the Peg3-DMR (differentially methylated region). (J:245745)
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Usp29 Mutation:  117 strains or lines available
References
Original:  J:245745 Kim J, et al., Inversion of the imprinting control region of the Peg3 domain. PLoS One. 2017;12(7):e0181591
All:  1 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
05/21/2024
MGI 6.23
The Jackson Laboratory