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Gene Expression Data
Assay Details
Assay
Reference: J:157036 Charalambous M, et al., Maternally-inherited Grb10 reduces placental size and efficiency. Dev Biol. 2010 Jan 1;337(1):1-8
Assay type: Immunohistochemistry
MGI Accession ID: MGI:6258894
Gene symbol: Grb10
Gene name: growth factor receptor bound protein 10
Antibody: anti-Grb10
Results
Specimen E14.5 not shown: embryonic day 14.5 (more )
Structure Level Pattern Image Note
TS22: chorionic plate Present Expression largely confined to labyrinthine compartment and chorionic plate.
TS22: labyrinthine zone Present Expression largely confined to labyrinthine compartment and chorionic plate.

Specimen 2A fetal: embryonic day 17.5 (more )
Structure Level Pattern Image Note
TS25: chorionic plate Present 2A Expression largely confined to labyrinthine compartment and chorionic plate.
TS25: labyrinthine zone Present 2A Expression largely confined to labyrinthine compartment and chorionic plate.

Specimen 2A maternal: postnatal adult (more )
Structure Level Pattern Image Note
TS28: decidua Weak 2A Occasional weak expression in maternal deciduum.

Specimen 2D fetal: embryonic day 17.5 (more )
Structure Level Pattern Image Note
TS25: capillary endothelium Present 2D Expression in fetal endothelium.
TS25: labyrinthine zone Present Regionally restricted 2D Expression in at least one of the 3 trophoblast layers of the labyrinth.
TS25: spongiotrophoblast Absent 2D No expression in spongiotrophoblast, glycogen cells and giant cells.
TS25: trophoblast giant cell Absent 2D No expression in spongiotrophoblast, glycogen cells and giant cells.

Specimen 3A +/+: embryonic day 17.5 (more )
Structure Level Pattern Image Note
TS25: hemotrichorial placental membrane Strong Regionally restricted 3A +/+ High levels of expression in membrane of endothelium apposed to fetal circulation.
TS25: labyrinthine zone Weak Regionally restricted 3A +/+ Lower levels of expression in labyrinthine trophoblast (close to large trophoblast nuclei).

Specimen 3A delta2-4/+: embryonic day 17.5; Grb10Gt(Betageo)1Ward/Grb10+ (more )
Note: Maternal transmission of deletion.
Structure Level Pattern Image Note
TS25: capillary endothelium Weak 3A Grb10delta2-4/+ Authors report relatively less abundant expression in the endothelial compartment.
TS25: labyrinthine zone Present Regionally restricted 3A Grb10delta2-4/+ Expression in labyrinthine trophoblast.

Specimen 3A +/delta2-4: embryonic day 17.5; Grb10Gt(Betageo)1Ward/Grb10+ (more )
Note: Paternal transmission of deletion.
Structure Level Pattern Image Note
TS25: capillary endothelium Strong 3A +/Grb10delta2-4 Abundant expression in endothelium.
TS25: labyrinthine zone Weak Regionally restricted 3A +/Grb10delta2-4 Weak expression in trophoblast.


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
03/25/2025
MGI 6.24
The Jackson Laboratory