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Gene Expression Data
Assay Details
Assay
Reference: J:265842 Palagano E, et al., Mutations in the Neuroblastoma Amplified Sequence gene in a family affected by Acrofrontofacionasal Dysostosis type 1. Bone. 2018 Sep;114:125-136
Assay type: Immunohistochemistry
MGI Accession ID: MGI:6258853
Gene symbol: Nbas
Gene name: neuroblastoma amplified sequence
Antibody: anti-NBAS
Detection system: Secondary antibody coupled to horseradish peroxidase
Results
Specimen 3a E11.5 top: embryonic day 11.5 (more )
Structure Level Pattern Image Note
TS19: limb Present Diffuse 3a E11.5 top

Specimen 3a E11.5 bottom: embryonic day 11.5 (more )
Structure Level Pattern Image Note
TS19: brain Present Diffuse 3a E11.5 bottom
TS19: dorsal root ganglion Present Diffuse 3a E11.5 bottom
TS19: neural tube Present Diffuse 3a E11.5 bottom

Specimen 3a E13.5 top: embryonic day 13.5 (more )
Structure Level Pattern Image Note
TS21: limb digit Present 3a E13.5 top
TS21: limb epithelium Present 3a E13.5 top
TS21: perichondrium Present Regionally restricted 3a E13.5 top Expression is in the perichondrial mesoderm of the limb.
TS21: limb cartilage condensation Weak Regionally restricted 3a E13.5 top

Specimen 3a E13.5 bottom: embryonic day 13.5 (more )
Structure Level Pattern Image Note
TS21: cortical plate Present 3a E13.5 bottom
TS21: ganglionic eminence Present 3a E13.5 bottom

Specimen 3b top: embryonic day 16.5 (more )
Structure Level Pattern Image Note
TS24: periosteum Present 3b top
TS24: vertebral cartilage condensation Present Regionally restricted 3b top Expression is in chondrocytes.

Specimen 3b bottom: embryonic day 16.5 (more )
Structure Level Pattern Image Note
TS24: periosteum Present 3b bottom
TS24: vertebral cartilage condensation Present Regionally restricted 3b bottom Expression is in chondrocytes.

Specimen 4: embryonic day 16.5 (more )
Structure Level Pattern Image Note
TS24: limb cartilage condensation Present Regionally restricted 4_NBAS Expression is in immature chondrocytes and fibroarticular cartilage and is weak in osteoblasts.
TS24: axial skeleton Present 4_NBAS
TS24: connective tissue Present Regionally restricted 4_NBAS Expression is in tendons.
TS24: perichondrium Weak Regionally restricted 4_NBAS
TS24: periosteum Weak Regionally restricted 4_NBAS

Specimen S3b: embryonic day 13.5 (more )
Structure Level Pattern Image Note
TS21: cerebral cortex Present S3b
TS21: ganglionic eminence Present S3b

Specimen S3c: embryonic day 13.5 (more )
Structure Level Pattern Image Note
TS21: retina Present S3c
TS21: tooth Present S3c

Specimen S3d: embryonic day 16.5 (more )
Structure Level Pattern Image Note
TS24: gonad Present S3d
TS24: liver Present S3d
TS24: lung Present S3d
TS24: metanephros Present S3d
TS24: spleen Present S3d
TS24: stomach Present S3d

Specimen S4: embryonic day 16.5 (more )
Structure Level Pattern Image Note
TS24: limb cartilage condensation Present Regionally restricted S4_NBAS Expression is in hypertrophic chondrocytes.
TS24: axial skeleton Present S4_NBAS
TS24: periosteum Present S4_NBAS
TS24: connective tissue Present Regionally restricted S4_NBAS Expression is in tendons.


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
03/19/2024
MGI 6.23
The Jackson Laboratory