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Gene Expression Data
Assay Details
Assay
Reference: J:157035 Fisher CL, et al., Additional sex combs-like 1 belongs to the enhancer of trithorax and polycomb group and genetically interacts with Cbx2 in mice. Dev Biol. 2010 Jan 1;337(1):9-15
Assay type: RNA in situ
MGI Accession ID: MGI:6258762
Gene symbol: Hoxc8
Gene name: homeobox C8
Probe: Hoxc8 probe12
Probe preparation: Antisense labelled with digoxigenin RNA
Results
Specimen 3 Hoxc8 +/+: embryonic day 10.5 (more )
Structure Level Pattern Image Note
TS17: future spinal cord Present 3_Hoxc8 +/+
TS17: paraxial mesenchyme Present 3_Hoxc8 +/+

Specimen 3 Hoxc8 tm1Bc/tm1Bc: embryonic day 10.5; Asxl1tm1Bc/Asxl1tm1Bc (more )
Structure Level Pattern Image Note
TS17: future spinal cord Strong Regionally restricted 3_Hoxc8 tm1Bc/tm1Bc Overall intensity of expression is much greater in mutant embryos than in wild-type. Expression is shifted anteriorly in ectoderm and mesoderm in mutant embryos by one somite, and expression can be detected more caudally than in wild-type.
TS17: paraxial mesenchyme Strong Regionally restricted 3_Hoxc8 tm1Bc/tm1Bc Overall intensity of expression is much greater in mutant embryos than in wild-type. Expression is shifted anteriorly in ectoderm and mesoderm in mutant embryos by one somite, and expression can be detected more caudally than in wild-type.


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/30/2024
MGI 6.23
The Jackson Laboratory