Summary | Transgene origin | Transgene description | Recombinase activity | Find Mice (IMSR) | References

Symbol:	Tg(Pthlh-cre/ERT2)909Nono
Name:	transgene insertion 909, Noriaki Ono
MGI ID:	MGI:6257033
Synonyms:	Pthrp-creER
Transgene:	Tg(Pthlh-cre/ERT2)909Nono  Location: unknown
Alliance:	Tg(Pthlh-cre/ERT2)909Nono page

Strain of Origin:

(C57BL/6 x SJL)F1

Transgene Type:    Transgenic (Inducible, Recombinase) Inducer:    tamoxifen Mutation:    Insertion   Tg(Pthlh-cre/ERT2)909Nono expression driven by 1 gene Transgene expression driven by: Organism Driver Gene Note mouse Pthlh (MGI:97800)   Mutation details: A bacterial artificial chromosome (BAC) library (CHORI) was used to obtain a BAC (#RP23-27F7) containing the entire mouse parathyroid hormone-like peptide (Pthlh) gene. This BAC was modified to replace the native start codon of the Pthlh gene with a cre/ERT2 fusion gene (Cre recombinase fused to a human estrogen receptor ligand-binding domain), followed by an SV40 polyadenylation sequence. (J:266751)

Activity:	Tissue activity of this recombinase allele
Driver:	Pthlh (mouse) Summary of all recombinase alleles driven by Pthlh. Comparative matrix view of recombinase activities Alliance mouse Pthlh gene page

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 1 strain available      Cell Lines: 0 lines available

Original:	J:266751 Mizuhashi K, et al., Resting zone of the growth plate houses a unique class of skeletal stem cells. Nature. 2018 Nov;563(7730):254-258
All:	4 reference(s)