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Gene Expression Data
Assay Details
Assay
Reference: J:248190 Chen K, et al., Spatio-temporal expression patterns of Wnt signaling pathway during the development of temporomandibular condylar cartilage. Gene Expr Patterns. 2017 Nov;25-26:149-158
Assay type: Immunohistochemistry
MGI Accession ID: MGI:6251542
Gene symbol: Lef1
Gene name: lymphoid enhancer binding factor 1
Antibody: Anti-Lef1 (LS-C37241)
Detection system: Biotinylated secondary antibody/[Strept]avidin coupled to horseradish peroxidase
Results
Specimen 9 E14.5: embryonic day 14.5 (more )
Structure Level Pattern Image Note
TS22: mandible ramus Present Regionally restricted 9_E14.5(A) , 9_E14.5 Expression was detected during mesenchymal condensation of the developing condylar cartilage.

Specimen 9 E15.5: embryonic day 15.5 (more )
Structure Level Pattern Image Note
TS23: mandible ramus Present Regionally restricted 9_E15.5(A) , 9_E15.5 Expression was widely distributed in the cytoplasm of the undifferentiated mesenchymal cells of the developing condylar cartilage.

Specimen 9 E16.5: embryonic day 16.5 (more )
Structure Level Pattern Image Note
TS24: mandible condylar process Present Regionally restricted 9_E16.5(A) , 9_E16.5 Expression was detected in the nucleus of differentiated chondrocytes in both the outer layer and central part of the condylar cartilage.

Specimen 9 P0: postnatal day 0 (more )
Structure Level Pattern Image Note
TS27: mandible condylar process Present Regionally restricted 9_P0(A) , 9_P0(B) , 9_P0 Expression was detected in the nucleus of proliferative and mineralized hypertrophic chondrocytes near the subchondral bone. Weak expression was detected in hypertrophic cells.

Specimen 9 P4: postnatal day 4 (more )
Structure Level Pattern Image Note
TS28: mandible condylar process Present Regionally restricted 9_P4(A) , 9_P4 Expression was detected in the proliferative chondrocytes. Weak expression was noted in the mineralized hypertrophic chondrocytes.

Specimen 9 P7: postnatal day 7 (more )
Structure Level Pattern Image Note
TS28: mandible condylar process Present Regionally restricted 9_P7 Expression was detected in mature chondrocytes.


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
03/18/2025
MGI 6.24
The Jackson Laboratory