Summary | Mutation origin | Mutation description | Find Mice (IMSR) | References

Symbol:	Washc5tm1.1Ccrs
Name:	WASH complex subunit 5; targeted mutation 1.1, Christoph S Clemen and Rolf Schroder
MGI ID:	MGI:6246601
Synonyms:	StrN471D, Strutm1.1Ccrs
Gene:	Washc5  Location: Chr15:59203846-59246016 bp, - strand  Genetic Position: Chr15, 25.17 cM
Alliance:	Washc5tm1.1Ccrs page

Germline Transmission:	Earliest citation of germline transmission: J:265574
Parent Cell Line:	Not Specified (ES Cell)
Strain of Origin:	129S2/SvPas

Allele Type:    Targeted (Not Specified) Mutations:    Insertion, Nucleotide substitutions   Mutation details: An N471D mutation (AAT to GAC) was inserted at position 1411 to 1413 and a floxed neo cassette was also inserted via homologous recombination. Cre-mediated recombination removed the neo cassette. (J:265574)

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Washc5 Mutation:	57 strains or lines available

Original:	J:265574 Song L, et al., Expression of N471D strumpellin leads to defects in the endolysosomal system. Dis Model Mech. 2018 Sep 13;11(9):dmm033449
All:	1 reference(s)