Tg(L1CAM)M2Pealt
Transgene Detail
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| Symbol: |
Tg(L1CAM)M2Pealt |
| Name: |
transgene insertion M2, Peter Altevogt |
| MGI ID: |
MGI:6246484 |
| Transgene: |
Tg(L1CAM)M2Pealt Location: unknown
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| Alliance: |
Tg(L1CAM)M2Pealt page
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| Strain of Origin: |
Not Specified
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| Transgene Type: |
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Transgenic (Inserted expressed sequence) |
| Mutation: |
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Insertion
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Tg(L1CAM)M2Pealt expresses
1 gene
Transgene expresses:
| Organism |
Expressed Gene |
Homolog in Mouse |
Note |
| human |
L1CAM (3897) |
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Tg(L1CAM)M2Pealt expression driven by
1 gene
Transgene expression driven by:
| Organism |
Driver Gene |
Homolog in Mouse |
Note |
| human |
L1CAM (3897) |
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Mutation details: The transgene contains the complete genomic human L1CAM sequence with large portion of the 3' and 5' sequences encompassing 180,000 bp. Three lines (M2, M3 and F4; with decreasing expression) were generated.
(J:219237)
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| Mouse strains and cell lines
available from the International Mouse Strain Resource
(IMSR) |
| Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available
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| Original: |
J:219237 Doberstein K, et al., Antibody therapy to human L1CAM in a transgenic mouse model blocks local tumor growth but induces EMT. Int J Cancer. 2015 Mar 1;136(5):E326-39 |
| All: |
1 reference(s) |
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Analysis Tools
