Summary | Transgene origin | Transgene description | Find Mice (IMSR) | References

Symbol:	Tg(L1CAM)F4Pealt
Name:	transgene insertion F4, Peter Altevogt
MGI ID:	MGI:6246486
Transgene:	Tg(L1CAM)F4Pealt  Location: unknown
Alliance:	Tg(L1CAM)F4Pealt page

Strain of Origin:

Not Specified

Transgene Type:    Transgenic (Inserted expressed sequence) Mutation:    Insertion   Tg(L1CAM)F4Pealt expresses 1 gene Transgene expresses: Organism Expressed Gene Homolog in Mouse Note human L1CAM (3897) L1cam  (MGI:96721)   Tg(L1CAM)F4Pealt expression driven by 1 gene Transgene expression driven by: Organism Driver Gene Homolog in Mouse Note human L1CAM (3897) L1cam  (MGI:96721)   Mutation details: The transgene contains the complete genomic human L1CAM sequence with large portion of the 3' and 5' sequences encompassing 180,000 bp. Three lines (M2, M3 and F4; with decreasing expression) were generated. (J:219237)

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 0 strains available      Cell Lines: 0 lines available

Original:	J:219237 Doberstein K, et al., Antibody therapy to human L1CAM in a transgenic mouse model blocks local tumor growth but induces EMT. Int J Cancer. 2015 Mar 1;136(5):E326-39
All:	1 reference(s)