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Gene Expression Data
Assay Details
Assay
Reference: J:26778 Kurihara Y, et al., Aortic arch malformations and ventricular septal defect in mice deficient in endothelin-1 [see comments]. J Clin Invest. 1995 Jul;96(1):293-300
Assay type: RNA in situ
MGI Accession ID: MGI:6236257
Gene symbol: Edn1
Gene name: endothelin 1
Probe: ET-1 probe4
Probe preparation: Antisense labelled with digoxigenin RNA
Visualized with: Alkaline phosphatase
Results
Specimen 3A: embryonic day 10.0 (more )
Structure Level Pattern Image Note
TS16: 1st branchial arch ectoderm Strong 3A
TS16: dorsal aorta Strong 3A
TS16: outflow tract Strong 3A
Specimen 3B: embryonic day 10.0 (more )
Structure Level Pattern Image Note
TS16: outflow tract Strong Regionally restricted 3B High expression in endocardium of outflow tract.
TS16: 1st arch artery Strong Regionally restricted 3B High expression in endothelium of first pharyngeal arch artery.
TS16: 1st branchial arch ectoderm Strong 3B
Specimen 3C: embryonic day 11.5 (more )
Structure Level Pattern Image Note
TS19: outflow tract Strong Regionally restricted 3C High expression in conotruncal region in a spiral pattern.
Specimen 3D: embryonic day 11.5 (more )
Structure Level Pattern Image Note
TS19: endocardial lining Present 3D Expression predominantly in endocardium.
TS19: endocardial cushion Present Regionally restricted 3D Expression in mesenchyme of endocardial cushion.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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03/25/2025
MGI 6.24 		The Jackson Laboratory