Summary | Mutation origin | Mutation description | Find Mice (IMSR) | References

Symbol:	Xcl1tm1.2Ksho
Name:	chemokine (C motif) ligand 1; targeted mutation 2.1, Tsuneyasu Kaisho
MGI ID:	MGI:6220923
Gene:	Xcl1  Location: Chr1:164759216-164763094 bp, - strand  Genetic Position: Chr1, 72.26 cM
Alliance:	Xcl1tm1.2Ksho page

Germline Transmission:	Earliest citation of germline transmission: J:235786
Parent Cell Line:	Bruce 4 (ES Cell)
Strain of Origin:	B6.Cg-Thy1a

Allele Type:    Targeted (Null/knockout) Mutations:    Insertion, Intragenic deletion   Mutation details: An FRT-flanked neomycin resistance cassette with a 5' loxP site was inserted upstream of exon 2. An additional loxP site was inserted downstream of exon 3. Flp-mediated recombination removed the slection cassette and left exons 2 and 3 floxed. Cre-mediated recombination removed exons 2 and 3. (J:235786)

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Xcl1 Mutation:	10 strains or lines available

Original:	J:235786 Ohta T, et al., Crucial roles of XCR1-expressing dendritic cells and the XCR1-XCL1 chemokine axis in intestinal immune homeostasis. Sci Rep. 2016 Mar 23;6:23505
All:	1 reference(s)