Tg(Tcra,Tcrb)24Litt
Transgene Detail
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| Symbol: |
Tg(Tcra,Tcrb)24Litt |
| Name: |
transgene insertion 24, Dan R Littman |
| MGI ID: |
MGI:6220465 |
| Synonyms: |
HH5-1tg |
| Transgene: |
Tg(Tcra,Tcrb)24Litt Location: unknown
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| Alliance: |
Tg(Tcra,Tcrb)24Litt page
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| Transgene Type: |
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Transgenic (Inserted expressed sequence) |
| Mutation: |
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Insertion
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Tg(Tcra,Tcrb)24Litt expresses
2 genes
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Mutation details: TCR (Valpha; subset TRAV8-1 and Vbeta; subset TRBV13-2) sequences recognizing Helicobacter hepaticus-specific epitope GNAYISVLAHYGKNG (E1) were cloned into TCR transgenic vectors pTalpha; and pTbeta, which enable transcription under the control of the natural TCRalpha and -beta promoter/enhancer elements.
(J:261814)
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| Mouse strains and cell lines
available from the International Mouse Strain Resource
(IMSR) |
| Carrying this Mutation: |
Mouse Strains: 1 strain available
Cell Lines: 0 lines available
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| Original: |
J:261814 Xu M, et al., c-MAF-dependent regulatory T cells mediate immunological tolerance to a gut pathobiont. Nature. 2018 Feb 15;554(7692):373-377 |
| All: |
2 reference(s) |
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Analysis Tools
