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Gene Expression Data
Assay Details
Assay
Reference: J:153643 Self M, et al., Six2 activity is required for the formation of the mammalian pyloric sphincter. Dev Biol. 2009 Oct 15;334(2):409-17
Assay type: RNA in situ
MGI Accession ID: MGI:6214818
Gene symbol: Nkx2-5
Gene name: NK2 homeobox 5
Results
Specimen 5A: embryonic day 12.5 (more )
Structure Level Pattern Image Note
TS20: stomach pyloric region mesenchyme Present Regionally restricted 5A Ring of expression in mesenchyme in presumptive pyloric sphincter region.
Specimen 5B: embryonic day 12.5; Six2tm1Gco/Six2tm1Gco (more )
Structure Level Pattern Image Note
TS20: stomach pyloric region mesenchyme Present Regionally restricted 5B Expression domain in presumptive pyloric sphincter region is narrower than that seen in wildtype embryos.
Specimen 5C: embryonic day 14.5 (more )
Structure Level Pattern Image Note
TS22: stomach pyloric region mesenchyme Present Regionally restricted 5C Expression remains in presumptive pyloric sphincter region.
Specimen 5D: embryonic day 14.5; Six2tm1Gco/Six2tm1Gco (more )
Structure Level Pattern Image Note
TS22: stomach pyloric region mesenchyme Present Regionally restricted 5D Authors no obvious differences in expression in the pyloric sphincter region of wildtype and mutant stomachs.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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03/25/2025
MGI 6.24 		The Jackson Laboratory