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Gene Expression Data
Assay Details
Assay
Reference: J:258981 Hagey DW, et al., SOX2 regulates common and specific stem cell features in the CNS and endoderm derived organs. PLoS Genet. 2018 Feb;14(2):e1007224
Assay type: Immunohistochemistry
MGI Accession ID: MGI:6209832
Gene symbol: Sox2
Gene name: SRY (sex determining region Y)-box 2
Antibody: anti-Sox2
Results
Specimen 1B upper left: embryonic day 11.5 (more )
Note: Data was summarized in Fig. S1A. Double labeled: green - Sox2; red - Mki67 (assay MGI:6214821).
Structure Level Pattern Image Note
TS19: brain Present 1B upper left The vast majority of neural cells expressing the proliferation marker Mki67 were Sox2+.
Specimen 1B upper right: embryonic day 11.5 (more )
Note: Data was summarized in Fig. S1A. Double labeled: green - Sox2; red - Mki67 (assay MGI:6214821).
Structure Level Pattern Image Note
TS19: future spinal cord Present 1B upper right The vast majority of neural cells expressing the proliferation marker Mki67 were Sox2+.
Specimen 1B lower left: embryonic day 11.5 (more )
Note: Data was summarized in Fig. S1A. Double labeled: green - Sox2; red - Mki67 (assay MGI:6214821).
Structure Level Pattern Image Note
TS19: stomach epithelium Present 1B lower left The vast majority of endodermal cells expressing the proliferation marker Mki67 were Sox2+.
Specimen 1B lower right: embryonic day 11.5 (more )
Note: Data was summarized in Fig. S1A. Double labeled: green - Sox2; red - Mki67 (assay MGI:6214821).
Structure Level Pattern Image Note
TS19: lung epithelium Present 1B lower right The vast majority of endodermal cells expressing the proliferation marker Mki67 were Sox2+.
Specimen 4A: embryonic day 11.5 (more )
Note: Double labeled: green - Sox2; red - BrdU.
Structure Level Pattern Image Note
TS19: future spinal cord Present 4A The fraction of cells expressing low levels of Sox2 that were labelled by BrdU was 1.6-times greater than that of the cells expressing high levels of Sox2.
Specimen 4B upper left: embryonic day 11.5 (more )
Note: Anterior stomach. Double labeled: green - Sox2; red - BrdU.
Structure Level Pattern Image Note
TS19: stomach epithelium Present 4B upper left
Specimen 4B upper right: embryonic day 15.5 (more )
Note: Anterior stomach. Double labeled: green - Sox2; red - BrdU.
Structure Level Pattern Image Note
TS23: stomach epithelium Present 4B upper right Expression and the fraction of BrdU+ cells did not change through development in the anterior stomach.
Specimen 4B lower left: embryonic day 11.5 (more )
Note: Posterior stomach. Double labeled: green - Sox2; red - BrdU.
Structure Level Pattern Image Note
TS19: stomach epithelium Present 4B lower left
Specimen 4B lower right: embryonic day 15.5 (more )
Note: Posterior stomach. Double labeled: green - Sox2; red - BrdU.
Structure Level Pattern Image Note
TS23: stomach epithelium Present 4B lower right Decreased expression in the posterior stomach was paralleled by a significant increase in the fraction of BrdU+ endodermal precursor cells and the formation of a striated, undulating epithelium.
Specimen not shown: embryonic day 13.5 (more )
Note: Double labeled: green - Sox2; red - BrdU.
Structure Level Pattern Image Note
TS21: stomach epithelium Present Non-Uniform Decreased expression in the posterior stomach was paralleled by a significant increase in the fraction of BrdU+ endodermal precursor cells and the formation of a striated, undulating epithelium. Expression and the fraction of BrdU+ cells did not change through development in the anterior stomach.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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03/25/2025
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