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Gene Expression Data
Assay Details
Assay
Reference: J:149254 Caton J, et al., Enamel-free teeth: Tbx1 deletion affects amelogenesis in rodent incisors. Dev Biol. 2009 Apr 15;328(2):493-505
Assay type: RNA in situ
MGI Accession ID: MGI:6209568
Gene symbol: Amelx
Gene name: amelogenin, X-linked
Probe: Amelx probe2
Probe preparation: Antisense labelled with digoxigenin RNA
Results
Specimen 9A wt E18.5 maxillary incisor: embryonic day 18.5 (more )
Structure Level Pattern Image Note
TS26: upper jaw incisor epithelium Strong Regionally restricted 9A wt E18.5 maxillary Authors report stronger expression in wildtype than in mutant incisors. Strong expression in cells of inner dental epithelium that differentiate into ameloblasts.

Specimen 9A -/- E18.5 maxillary incisor: embryonic day 18.5; Folh1tm1Nle/Folh1tm1Nle (more )
Structure Level Pattern Image Note
TS26: upper jaw incisor epithelium Absent 9A -/- E18.5 maxillary Expression either absent or weakly expressed in incisors of Tbx1 null mutants.

Specimen 9A -/- E18.75 maxillary incisor: embryonic day 18.75; Folh1tm1Nle/Folh1tm1Nle (more )
Structure Level Pattern Image Note
TS26: upper jaw incisor epithelium Weak 9A -/- E18.75 maxillary Weaker expression in maxillary vs. mandibular incisors.

Specimen 9A wt E18.5 mandibular incisor: embryonic day 18.5 (more )
Structure Level Pattern Image Note
TS26: lower jaw incisor epithelium Strong Regionally restricted 9A wt E18.5 mandibular Authors report stronger expression in wildtype than in mutant incisors. Strong expression in cells of inner dental epithelium that differentiate into ameloblasts.

Specimen 9A -/- E18.5 mandibular incisor: embryonic day 18.5; Folh1tm1Nle/Folh1tm1Nle (more )
Structure Level Pattern Image Note
TS26: lower jaw incisor epithelium Present 9A -/- E18.5 mandibular Stronger expression in mutant mandibular incisors compared to mutant maxillary incisors.

Specimen 9A -/- E18.75 mandibular incisor: embryonic day 18.75; Folh1tm1Nle/Folh1tm1Nle (more )
Structure Level Pattern Image Note
TS26: lower jaw incisor epithelium Present 9A -/- E18.75 mandibular Stronger expression in mutant mandibular incisors compared to mutant maxillary incisors.

Specimen 10C: postnatal day 2; Spry2tm1.1Mrt/Spry2+, Spry4tm1.2Mrt/Spry4tm1.2Mrt (more )
Structure Level Pattern Image Note
TS27: incisor epithelium Present Regionally restricted 10C Expression on both lingual and labial sides.


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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/23/2024
MGI 6.23
The Jackson Laboratory