Summary | Mutation origin | Mutation description | Find Mice (IMSR) | References

Symbol:	Kif21bem1Adiuj
Name:	kinesin family member 21B; endonuclease-mediated mutation 1, MODEL-AD Center
MGI ID:	MGI:6202982
Gene:	Kif21b  Location: Chr1:136059127-136105736 bp, + strand  Genetic Position: Chr1, 59.61 cM
Alliance:	Kif21bem1Adiuj page

Strain of Origin:

B6(SJL)-Apoetm1.1(APOE*4)Adiuj Trem2em1Adiuj/J

Allele Type:    Endonuclease-mediated (Not Specified) Mutation:    Nucleotide substitutions   Mutation details: Plasmids encoding a single guide RNA designed to introduce the T82T point mutation, rs7556510 SNP (ACG to ACA), knock-in mutation into the gene and the cas9 nuclease were introduced into the cytoplasm of fertilized eggs with well recognized pronuclei. (J:101977)

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Kif21b Mutation:	88 strains or lines available

Original:	J:101977 The Jackson Laboratory, Information obtained from The Jackson Laboratory, Bar Harbor, ME. Unpublished. 2005-2017;
All:	1 reference(s)