Reporter:	lacZ
	Direct Detection

Structure	Level	Pattern	Image	Note
TS14: trigeminal neural crest	Present			Expression first detected in trigeminal (V) ganglion at E8.75 (12-14 somites).

Structure	Level	Pattern	Image	Note
TS14: facio-acoustic neural crest	Present			Authors report expression in geniculate (VII) and vestibulocochlear (VIII) ganglia at E9.25 (2224 somites stage).
TS14: epibranchial placode	Present			Authors report expression in petrosal (IX) and nodose (X) ganglia at E9.25 (2224 somites stage).
TS14: petrosal placode	Present			Authors report expression in petrosal (IX) and nodose (X) ganglia at E9.25 (2224 somites stage).

Structure	Level	Pattern	Image	Note
TS15: facio-acoustic preganglion complex	Present	Regionally restricted	1A	Expression in geniculate (facial) and vestibulocochlear (acoustic) ganglia,

Structure	Level	Pattern	Image	Note
TS15: facio-acoustic preganglion complex	Weak	Regionally restricted	1A inset	Weak expression in aggregating neurons of developing vestibulocochlear ganglion. Expression only in cells that had aggregated in the ganglion.
TS15: otocyst	Absent		1A inset	Expression only in cells that had left the otic vesicle.

Structure	Level	Pattern	Image	Note
TS17: acoustic ganglion	Strong		1B	Authors state expression level increased during next few days. Strongest expression at E10.5 in geniculate (VII) and vestibulocochlear (VIII) ganglia.
TS17: facial ganglion	Strong		1B	Authors state expression level increased during next few days. Strongest expression at E10.5 in geniculate (VII) and vestibulocochlear (VIII) ganglia.

Structure	Level	Pattern	Image	Note
TS19: acoustic ganglion	Present		1C	From E11.5 downwards, levels of expression continuously decreased but could still be detected until the end of fetal development.
TS19: facial ganglion	Present		1C	From E11.5 downwards, levels of expression continuously decreased but could still be detected until the end of fetal development.

Structure	Level	Pattern	Image	Note
TS26: inner ear	Strong	Regionally restricted	2A	Relatively strong expression in all sensory organs of inner ear.
TS26: macula of saccule	Strong		2A
TS26: macula of utricle	Strong		2A
TS26: semicircular canal	Strong	Regionally restricted	2A	Expression in all cristae of semicircular canals.
TS26: organ of Corti	Strong	Regionally restricted	2A	Expression in inner and outer hair cells of cochlea

Structure	Level	Pattern	Image	Note
TS26: vestibulo-cochlear ganglion	Weak		2B	Low level expression in vestibulo-cochlear ganglion. Authors expression in cells separate from proliferating cells stained for BrdU.

Structure	Level	Pattern	Image	Note
TS26: organ of Corti	Present	Regionally restricted	2B inset	Expression in inner and outer sensory hair cells of the organ of Corti.

Structure	Level	Pattern	Image	Note
TS26: vestibulo-cochlear ganglion	Weak	Regionally restricted	2C	Low level expression in vestibulo-cochlear ganglion. Expression restricted to differentiated neurons.

Structure	Level	Pattern	Image	Note
TS26: vestibulo-cochlear ganglion	Present	Regionally restricted	2C inset	Expression localized to differentiating neurons within the vestibulococlear ganglion.

Structure	Level	Pattern	Image	Note
TS26: organ of Corti	Present	Regionally restricted	2D	Expression restricted to rows of inner and outer hair cells.

Structure	Level	Pattern	Image	Note
TS26: organ of Corti	Present		2D inset

Structure	Level	Pattern	Image	Note
TS26: vestibulo-cochlear ganglion	Weak	Regionally restricted	2F	Low level expression in vestibulo-cochlear ganglion. Expression restricted to differentiated neurons.

Structure	Level	Pattern	Image	Note
TS26: organ of Corti	Present	Regionally restricted	2F inset	Expression localized to inner and outer hair cells.

Structure	Level	Pattern	Image	Note
TS28: organ of Corti	Present	Regionally restricted	3A	Expression in all inner and outer sensory hair cells of cochlea

Structure	Level	Pattern	Image	Note
TS28: organ of Corti	Present	Regionally restricted	3A inset	Expression in all inner and outer sensory hair cells of cochlea

Structure	Level	Pattern	Image	Note
TS28: organ of Corti	Present	Regionally restricted	3B	Expression in all inner and outer sensory hair cells of cochlea

Structure	Level	Pattern	Image	Note
TS28: posterior semicircular canal	Strong	Regionally restricted	3C	Expression confined to semicircular canal epithelium. No expression in supporting cells of canal epithelium.

Structure	Level	Pattern	Image	Note
TS28: posterior semicircular canal	Strong	Regionally restricted	3C inset	Expression confined to semicircular canal epithelium. No expression in supporting cells of canal epithelium.

Structure	Level	Pattern	Image	Note
TS28: semicircular canal	Present	Regionally restricted		Expression in sensory receptor cells of cristae of all three semicircular canals.

Structure	Level	Pattern	Image	Note
TS28: organ of Corti	Strong	Regionally restricted	3D	Relatively strong expression within apical turns of cochlea.

Structure	Level	Pattern	Image	Note
TS28: organ of Corti	Present	Regionally restricted	3E	Expression in only ~50% of inner and outer hair cells.

Structure	Level	Pattern	Image	Note
TS28: organ of Corti	Weak	Regionally restricted	3F	Expression confined to sensory receptor cells of cochlea. Weak expression in inner and outer hair cells.

Structure	Level	Pattern	Image	Note
TS28: inner ear	Absent

Structure	Level	Pattern	Image	Note
TS28: inner ear	Absent

Structure	Level	Pattern	Image	Note
TS17: acoustic ganglion	Present		4A
TS17: facial ganglion	Present		4A
TS17: trigeminal ganglion	Present		4A

Structure	Level	Pattern	Image	Note
TS17: acoustic ganglion	Present		4A inset

Structure	Level	Pattern	Image	Note
TS17: acoustic ganglion	Present		4B
TS17: facial ganglion	Present		4B
TS17: trigeminal ganglion	Present		4B

Structure	Level	Pattern	Image	Note
TS17: acoustic ganglion	Weak	Regionally restricted	4B inset	Authors report significant reduction in number of expressing cells within vestibulocochlear ganglion.

Structure	Level	Pattern	Image	Note
TS17: acoustic ganglion	Present		4C
TS17: facial ganglion	Present		4C
TS17: trigeminal ganglion	Present		4C

Structure	Level	Pattern	Image	Note
TS17: acoustic ganglion	Weak	Regionally restricted	4C inset	Authors report significant reduction in number of expressing cells within vestibulocochlear ganglion.

Structure	Level	Pattern	Image	Note
TS22: neural retina	Present	Regionally restricted	6A	Authors report first expression detected in the ganglion cell layer at E14.5.

Structure	Level	Pattern	Image	Note
TS24: retina layer	Present	Regionally restricted	6C	Authors report expression in the ganglion cell layer.
TS24: retina outer nuclear layer	Strong		6C	Prominent expression at outer boundary of ventricular zone.
TS24: retina inner nuclear layer	Present	Scattered	6C	Expression in a few scattered cells within inner part of ventricular zone.

Structure	Level	Pattern	Image	Note
TS26: retina nuclear layer	Present	Regionally restricted	6E	Expression in cells at outer and inner borders of ventricular zone.
TS26: retina outer nuclear layer	Strong		6E	Strong expression in outer ventricular zone.

Structure	Level	Pattern	Image	Note
TS28: retina outer nuclear layer	Absent		6G	No expression in outer ventricular zone.
TS28: retina ganglion cell layer	Present		6G	Expression restricted to ganglion cell layer and inner nuclear layer of retina.
TS28: retina inner nuclear layer	Present		6G	Expression restricted to ganglion cell layer and inner nuclear layer of retina.

Structure	Level	Pattern	Image	Note
TS28: retina	Absent

Structure	Level	Pattern	Image	Note
TS26: retina	Present	Regionally restricted	6I	Expression restricted to postmitotic cells.

Structure	Level	Pattern	Image	Note
TS26: retina	Present	Regionally restricted	6J	Expression restricted to postmitotic cells.

Structure	Level	Pattern	Image	Note
TS26: retina outer nuclear layer	Present	Regionally restricted	6K	Expression in outer boundary of ventricular layer decreased in intensity at periphery of retina.

Structure	Level	Pattern	Image	Note
TS24: hair follicle	Present		7A	In anterior head region, expression in hair follicles in anterior head region.

Structure	Level	Pattern	Image	Note
TS24: hair follicle	Present		7A inset	Expression within hair follicles at E16.5 when hair follicles begin to mature and invaginate dermis.

Structure	Level	Pattern	Image	Note
TS26: head skin	Present	Regionally restricted	7B	Expression in cells in basal layer of skin in anterior head regions.

Structure	Level	Pattern	Image	Note
TS26: vibrissa follicle	Present		7B inset

Structure	Level	Pattern	Image	Note
TS26: vibrissa follicle	Present	Regionally restricted	7C	Expression concentrated around bulge region and base of vibrissa follicle.

Structure	Level	Pattern	Image	Note
TS26: hair outer root sheath	Present	Regionally restricted	7D	Authors report no colocalization of expression with BrdU in cells in outer hair sheet layer.

Structure	Level	Pattern	Image	Note
TS28: hair follicle	Present	Regionally restricted	7E	Expression still detectable in hair follicles in basal areas of skin.

Structure	Level	Pattern	Image	Note
TS26: skin	Present	Regionally restricted	7F	Expression in Merkel cells containing touch domes of skin.

Structure	Level	Pattern	Image	Note
TS26: skin	Present	Regionally restricted	7F inset	Expression in Merkel cells containing touch domes of skin.

Structure	Level	Pattern	Image	Note
TS26: skin	Present	Regionally restricted	7G	Expression in Merkel cells containing touch domes of skin.

Structure	Level	Pattern	Image	Note
TS28: taste bud	Present	Regionally restricted	7H	Expression in subset of taste buds.