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Gene Expression Data
Assay Details
Assay
Reference: J:265502 Kim ST, et al., The N-recognin UBR4 of the N-end rule pathway is required for neurogenesis and homeostasis of cell surface proteins. PLoS One. 2018;13(8):e0202260
Assay type: Immunohistochemistry
MGI Accession ID: MGI:6202035
Gene symbol: Cdh2
Gene name: cadherin 2
Antibody: anti-N-cadherin
Detection system: Secondary antibody coupled to Alexa Fluor 488
Results
Specimen 4F Yolk sac +/+: embryonic day 9.5 (more )
Structure Level Pattern Image Note
TS15: yolk sac Present Regionally restricted 4F Yolk sac +/+ Thin lines of expression along the plasma membrane.

Specimen 4F Yolk sac -/-: embryonic day 9.5; Ubr4tm1.1Ytkw/Ubr4tm1.1Ytkw (more )
Structure Level Pattern Image Note
TS15: yolk sac Ambiguous 4F Yolk sac -/- Expression markedly downregulated and disorganized.

Specimen 4F Neural tube +/+: embryonic day 9.5 (more )
Structure Level Pattern Image Note
TS15: central nervous system Present Regionally restricted 4F Neural tube +/+ Thin lines of expression along the plasma membrane.

Specimen 4F Neural tube -/-: embryonic day 9.5; Ubr4tm1.1Ytkw/Ubr4tm1.1Ytkw (more )
Structure Level Pattern Image Note
TS15: central nervous system Ambiguous 4F Neural tube -/- Expression markedly downregulated and disorganized.

Specimen 4F Septum transversum +/+: embryonic day 9.5 (more )
Structure Level Pattern Image Note
TS15: septum transversum Present Regionally restricted 4_Septum transversum +/+ Expression in mesenchymal cells.

Specimen 4F Septum transversum -/-: embryonic day 9.5; Ubr4tm1.1Ytkw/Ubr4tm1.1Ytkw (more )
Structure Level Pattern Image Note
TS15: septum transversum Present Regionally restricted 4FF Septum transversum -/- Authors state expression appeared normal in tissues that exhibited relatively mild null phenotypes.


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
03/25/2025
MGI 6.24
The Jackson Laboratory