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Gene Expression Data
Assay Details
Assay
Reference: J:166085 Bott RC, et al., KDR-LacZ-expressing cells are involved in ovarian and testis-specific vascular development, suggesting a role for VEGFA in the regulation of this vasculature. Cell Tissue Res. 2010 Oct;342(1):117-30
Assay type: In situ reporter (knock in)
MGI Accession ID: MGI:6201546
Gene symbol: Kdr
Gene name: kinase insert domain protein receptor
Reporter: lacZ
Antibody: anti-B-galactosidase (Abcam)
Detection system: Secondary antibody coupled to fluorescein
Results
Specimen 8a: embryonic day 17.0; Kdrtm1Jrt/Kdr+ (more )
Structure Level Pattern Image Note
TS25: germ cell of testis Present 8a
TS25: interstitium of the testis Strong 8a
Specimen 8b: postnatal day 20; Kdrtm1Jrt/Kdr+ (more )
Structure Cell Type Level Pattern Image Note
TS28: Leydig cell Leydig cell Present 8b
TS28: spermatid Present 8b Expression was detected in round spermatids.
Specimen 8c: postnatal day 60; Kdrtm1Jrt/Kdr+ (more )
Structure Level Pattern Image Note
TS28: spermatozoon Present 8c
Specimen 8d: postnatal day 60; Kdrtm1Jrt/Kdr+ (more )
Structure Level Pattern Image Note
TS28: spermatozoon Present 8d
Specimen 8e: embryonic day 17.0; Kdrtm1Jrt/Kdr+ (more )
Structure Level Pattern Image Note
TS25: ovary Present Regionally restricted 8e Expression was detected around oocytes within oocyte cysts.
Specimen 9a/c: embryonic day 17.0; Kdrtm1Jrt/Kdr+ (more )
Note: Double labeled: white - Kdr; green - Pecam1 (assay MGI:6201588).
Structure Cell Type Level Pattern Image Note
TS25: interstitium of the testis Present 9a , 9c
TS25: seminiferous cord Present 9a , 9c
TS25: Leydig cell Leydig cell Present 9a , 9c
Specimen 9d/f: embryonic day 17.0; Kdrtm1Jrt/Kdr+ (more )
Note: Double labeled: white - Kdr; green - Cdh5 (assay MGI:6201589).
Structure Cell Type Level Pattern Image Note
TS25: interstitium of the testis Present 9d , 9f
TS25: seminiferous cord Present 9d , 9f
TS25: Leydig cell Leydig cell Present 9d , 9f
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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03/25/2025
MGI 6.24 		The Jackson Laboratory