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Tg(Krt8-GFP,-HBEGF)4214Muth
Transgene Detail
Summary
Symbol: Tg(Krt8-GFP,-HBEGF)4214Muth
Name: transgene insertion 4214, Senthil Muthuswamy
MGI ID: MGI:6201419
Synonyms: K8.tGPD
Transgene: Tg(Krt8-GFP,-HBEGF)4214Muth  Location: unknown  
Alliance: Tg(Krt8-GFP,-HBEGF)4214Muth page
Transgene
origin
Strain of Origin:  FVB/N
Transgene
description
Transgene Type:    Transgenic (Inserted expressed sequence, Reporter)
Mutation:    Insertion
 
Tg(Krt8-GFP,-HBEGF)4214Muth expresses 1 gene
 
Mutation detailsThe transgenic construct was designed with a mouse keratin 8 promoter followed by a rabbit beta-globin intron driving co-expression of both a turbo green fluorescent protein (tGFP) and a suicide gene, chimpanzee diphtheria toxin receptor, separated by a P2A peptide plus a hygromycin selection cassette. The hygromycin cassette has been removed. tGFP is a fast-maturing short half-life turbo green fluorescent protein. (J:264089)
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 0 lines available
References
Original:  J:264089 Sonzogni O, et al., Reporters to mark and eliminate basal or luminal epithelial cells in culture and in vivo. PLoS Biol. 2018 Jun;16(6):e2004049
All:  1 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
01/06/2026
MGI 6.24
The Jackson Laboratory