About   Help   FAQ
Gene Expression Data
Assay Details
Assay
Reference: J:135338 Cirio MC, et al., Preimplantation expression of the somatic form of Dnmt1 suggests a role in the inheritance of genomic imprints. BMC Dev Biol. 2008;8:9
Assay type: Immunohistochemistry
MGI Accession ID: MGI:6201393
Gene symbol: Dnmt1
Gene name: DNA methyltransferase 1
Antibody: UPTC21
Detection system: Secondary antibody coupled to fluorescein
Assay notes: Antibody recognizes both the Dnmt1s and the Dnmt1o proteins, but mostly Dnmt1o.
Results
Specimen 3C +/+ PN3: embryonic day 0.5 (more )
Note: 1-cell embryo, pronuclear stage 3
Structure Level Pattern Image Note
TS1: 1-cell stage embryo Strong 3C left Only expressed in the cytoplasm, not in the pronuclei.

Specimen 3C +/+ PN4: embryonic day 0.5 (more )
Note: 1-cell embryo, pronuclear stage 4
Structure Level Pattern Image Note
TS1: 1-cell stage embryo Strong 3C right Only expressed in the cytoplasm, not in the pronuclei.


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support.
last database update
03/25/2025
MGI 6.24
The Jackson Laboratory