Tg(tetO-MAPT)21221Kha
Transgene Detail
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| Symbol: |
Tg(tetO-MAPT)21221Kha |
| Name: |
transgene insertion 21221, Karen Hsiao Ashe |
| MGI ID: |
MGI:6200597 |
| Synonyms: |
rTg21221, rTgWT, Tg(tetO-MAPT*wt)21221 |
| Transgene: |
Tg(tetO-MAPT)21221Kha Location: unknown
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| Alliance: |
Tg(tetO-MAPT)21221Kha page
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| Transgene Type: |
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Transgenic (Inducible) |
| Inducer: |
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doxycycline/tetracycline |
| Mutation: |
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Insertion
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Mutation details: The human four-repeat tau gene was placed downstream of the tetracycline-responsive (TRE or tetO) promoter and inserted into the context of the mouse prion protein gene (prnp) exons 2-3 transcribed but untranslated sequences.
(J:251724)
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| Mouse strains and cell lines
available from the International Mouse Strain Resource
(IMSR) |
| Carrying this Mutation: |
Mouse Strains: 1 strain available
Cell Lines: 0 lines available
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| Original: |
J:251724 Hoover BR, et al., Tau mislocalization to dendritic spines mediates synaptic dysfunction independently of neurodegeneration. Neuron. 2010 Dec 22;68(6):1067-81 |
| All: |
10 reference(s) |
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Analysis Tools
