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Gene Expression Data
Assay Details
Assay
Reference: J:264681 Koehler S, et al., Construction of a viral T2A-peptide based knock-in mouse model for enhanced Cre recombinase activity and fluorescent labeling of podocytes. Kidney Int. 2017 Jun;91(6):1510-1517
Assay type: In situ reporter (knock in)
MGI Accession ID: MGI:6200389
Gene symbol: Nphs2
Gene name: nephrosis 2, podocin
Reporter: Cre
Antibody: anti-cre (Novagen/EMD)
Results
Specimen 1e - 12 weeks: postnatal week 12; Nphs2tm1.1(icre)Ptb/Nphs2+ (more )
Note: Double labeled: green - nuclear-localized Nphs2 reporter (Cre); purple - membrane-localized Nphs2 reporter (mTomato; assay MGI:6202340).
Structure Level Pattern Image Note
TS28: Bowman's capsule of mature renal corpuscle Present Regionally restricted 1e 12 weeks merge , 1e 12 weeks Cre Expression is seen in the podocytes.
Specimen 1e - 6 months: postnatal month 6; Nphs2tm1.1(icre)Ptb/Nphs2+ (more )
Note: Double labeled: green - nuclear-localized Nphs2 reporter (Cre); purple - membrane-localized Nphs2 reporter (mTomato; assay MGI:6202340).
Structure Level Pattern Image Note
TS28: Bowman's capsule of mature renal corpuscle Present Regionally restricted 1e 6 months merge , 1e 6 months Cre Expression is seen in the podocytes.
Specimen 1e - 1 year: postnatal year 1; Nphs2tm1.1(icre)Ptb/Nphs2+ (more )
Note: Double labeled: green - nuclear-localized Nphs2 reporter (Cre); purple - membrane-localized Nphs2 reporter (mTomato; assay MGI:6202340).
Structure Level Pattern Image Note
TS28: Bowman's capsule of mature renal corpuscle Present Regionally restricted 1e 1 year merge , 1e 1 year Cre Expression is seen in the podocytes.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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04/16/2024
MGI 6.23 		The Jackson Laboratory