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Gene Expression Data
Assay Details
Assay
Reference: J:146147 Espinoza-Lewis RA, et al., Shox2 is essential for the differentiation of cardiac pacemaker cells by repressing Nkx2-5. Dev Biol. 2009 Mar 15;327(2):376-85
Assay type: RNA in situ
MGI Accession ID: MGI:6200242
Gene symbol: Shox2
Gene name: SHOX homeobox 2
Probe: Shox2 probe4
Probe preparation: Antisense RNA
Results
Specimen not shown: embryonic day 8.0 (more )
Structure Level Pattern Image Note
TS12: heart Absent

Specimen 1A: embryonic day 8.5 (more )
Structure Level Pattern Image Note
TS13: sinus venosus Present 1A Expression initially detected in at E8.5 in a restricted pattern at junction formed by common cardinal vein and common atrial chamber, the sinus venosus.

Specimen 1B: embryonic day 10.5 (more )
Structure Level Pattern Image Note
TS17: sinus venosus Present 1B Cardiac looping and remodeling brings sinus venosus to right side of heart.
TS17: sinoatrial node Present Regionally restricted 1B Expression gradually becomes restricted to dorsal wall of right atrium.
TS17: common atrial chamber right part venous valve Present Regionally restricted 1B Expression extends to sinus valves originating from sinus node.

Specimen 1C: embryonic day 11.5 (more )
Structure Level Pattern Image Note
TS19: sinoatrial node Present 1C Expression specifically restricted to sinoatrial node (SAN) and venous layers of sinus valves.
TS19: right atrium venous valve Present Regionally restricted 1C Expression specifically restricted to sinoatrial node (SAN) and venous layers of sinus valves.

Specimen 1D: embryonic day 12.5 (more )
Structure Level Pattern Image Note
TS20: sinoatrial node Present 1D Expression specifically restricted to sinoatrial node (SAN) and venous layers of sinus valves.
TS20: right atrium venous valve Present Regionally restricted 1D Expression specifically restricted to sinoatrial node (SAN) and venous layers of sinus valves.

Specimen 1E: embryonic day 16.5 (more )
Structure Level Pattern Image Note
TS24: sinoatrial node Present 1E Expression specifically restricted to sinoatrial node (SAN) and venous layers of sinus valves.
TS24: right atrium venous valve Present Regionally restricted 1E Expression specifically restricted to sinoatrial node (SAN) and venous layers of sinus valves.


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
03/25/2025
MGI 6.24
The Jackson Laboratory