Tg(tetO-Doc2b,-EGFP)#Dct
Transgene Detail
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| Symbol: |
Tg(tetO-Doc2b,-EGFP)#Dct |
| Name: |
transgene insertion, Debbie C Thurmond |
| MGI ID: |
MGI:6199045 |
| Synonyms: |
TRE-Doc2b |
| Transgene: |
Tg(tetO-Doc2b,-EGFP)#Dct Location: unknown
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| Alliance: |
Tg(tetO-Doc2b,-EGFP)#Dct page
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| Transgene Type: |
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Transgenic (Conditional ready, Inserted expressed sequence, Reporter) |
| Mutation: |
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Insertion
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Tg(tetO-Doc2b,-EGFP)#Dct expresses
1 gene
Transgene expresses:
| Organism |
Expressed Gene |
Homolog in Mouse |
Note |
| rat |
Doc2b (81820) |
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rat cDNA |
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Mutation details: The transgene construct comprises the following elements: the tetracycline response element (TRE) containing promoter tetO, the rat beta double C2 cDNA, sequence for a C-terminal Myc-His tag, an IRES, the EGFP fluorescent reporter gene, and poly(A) signal sequence. This allele, when co-expressed with an rTA or rtTA expressing allele, will express the inserted genes in a tetracycline/doxycycline inducible manner.
(J:264812)
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| Mouse strains and cell lines
available from the International Mouse Strain Resource
(IMSR) |
| Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available
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| Original: |
J:264812 Aslamy A, et al., Doc2b Protects beta-Cells Against Inflammatory Damage and Enhances Function. Diabetes. 2018 Jul;67(7):1332-1344 |
| All: |
1 reference(s) |
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Analysis Tools
