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Gene Expression Data
Assay Details
Assay
Reference: J:60228 Yuan B, et al., Inhibition of distal lung morphogenesis in Nkx2.1(-/-) embryos. Dev Dyn. 2000 Feb;217(2):180-90
Assay type: Immunohistochemistry
MGI Accession ID: MGI:6198601
Gene symbol: Nkx2-1
Gene name: NK2 homeobox 1
Antibody: Anti-Nkx2.1
Detection system: Biotinylated secondary antibody/[Strept]avidin coupled to horseradish peroxidase
Results
Specimen 2A: embryonic day 10.0 (more )
Structure Level Pattern Image Note
TS16: lung epithelium Present Widespread 2A Expressed in all the epithelial cells.

Specimen 2B: embryonic day 15.0 (more )
Structure Level Pattern Image Note
TS23: lung epithelium Present 2B Expressed in the nucleus of epithelial cells.

Specimen 2C: embryonic day 15.0 (more )
Structure Level Pattern Image Note
TS23: lung epithelium Present Regionally restricted 2C Expression was suppressed in a proximo-distal pattern, significantly diminished in the trachea and the mainstem bronchi.

Specimen 2D: postnatal day 2 (more )
Structure Level Pattern Image Note
TS27: alveolus epithelium Present Regionally restricted 2D Expressed in the progenitor of alveolar type II cells.


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
03/25/2025
MGI 6.24
The Jackson Laboratory