Gene Expression Data
Assay Details
Assay
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Reference:
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J:60228
Yuan B, et al., Inhibition of distal lung morphogenesis in Nkx2.1(-/-) embryos. Dev Dyn. 2000 Feb;217(2):180-90
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Assay type:
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Immunohistochemistry
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MGI Accession ID:
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MGI:6198601
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Gene symbol:
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Nkx2-1
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Gene name:
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NK2 homeobox 1
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Antibody:
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Anti-Nkx2.1
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Detection system:
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Biotinylated secondary antibody/[Strept]avidin coupled to horseradish peroxidase
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Results
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Specimen
2A:
embryonic day 10.0
(more )
Specimen
2A:
(close )
Genetic Background:
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Swiss Webster
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Age:
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embryonic day 10.0
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Age Note:
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Age of embryo at noon of plug day not specified in reference.
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Sex:
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Not Specified
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Type:
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section
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Fixation:
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Carnoy's Fixative
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Embedding:
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Paraffin
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Structure |
Level |
Pattern |
Image |
Note |
TS16: lung epithelium |
Present |
Widespread |
2A
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Expressed in all the epithelial cells.
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Specimen
2B:
embryonic day 15.0
(more )
Specimen
2B:
(close )
Genetic Background:
|
Swiss Webster
|
Age:
|
embryonic day 15.0
|
Age Note:
|
Age of embryo at noon of plug day not specified in reference.
|
Sex:
|
Not Specified
|
Type:
|
section
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Fixation:
|
Carnoy's Fixative
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Embedding:
|
Paraffin
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Specimen
2C:
embryonic day 15.0
(more )
Specimen
2C:
(close )
Genetic Background:
|
Swiss Webster
|
Age:
|
embryonic day 15.0
|
Age Note:
|
Age of embryo at noon of plug day not specified in reference.
|
Sex:
|
Not Specified
|
Type:
|
section
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Fixation:
|
Carnoy's Fixative
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Embedding:
|
Paraffin
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Structure |
Level |
Pattern |
Image |
Note |
TS23: lung epithelium |
Present |
Regionally restricted |
2C
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Expression was suppressed in a proximo-distal pattern, significantly diminished in the trachea and the mainstem bronchi.
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Specimen
2D:
postnatal day 2
(more )
Specimen
2D:
(close )
Genetic Background:
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Swiss Webster
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Age:
|
postnatal day 2
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Sex:
|
Not Specified
|
Type:
|
section
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Fixation:
|
Carnoy's Fixative
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Embedding:
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Paraffin
|
Structure |
Level |
Pattern |
Image |
Note |
TS27: alveolus epithelium |
Present |
Regionally restricted |
2D
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Expressed in the progenitor of alveolar type II cells.
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