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Gene Expression Data
Assay Details
Assay
Reference: J:143541 Chen L, et al., Rac1 deficiency in the forebrain results in neural progenitor reduction and microcephaly. Dev Biol. 2009 Jan 1;325(1):162-70
Assay type: Immunohistochemistry
MGI Accession ID: MGI:6197796
Gene symbol: Ppp1r1b
Gene name: protein phosphatase 1, regulatory inhibitor subunit 1B
Antibody: anti-DARPP-32
Detection system: Biotinylated secondary antibody/[Strept]avidin coupled to horseradish peroxidase
Results
Specimen 5B: embryonic day 18.5 (more )
Structure Level Pattern Image Note
TS26: corpus striatum Present Regionally restricted 5B Expression in striatal projection neurons in 'patch' compartment.
Specimen 5E: embryonic day 18.5; Rac1tm1Djk/Rac1tm1Djk, Foxg1tm1(cre)Skm/Foxg1+ (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS26: corpus striatum Ambiguous 5E Authors report greatly decreased expression in mutant compared to control embryos.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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04/23/2024
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