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Gene Expression Data
Assay Details
Assay
Reference: J:143541 Chen L, et al., Rac1 deficiency in the forebrain results in neural progenitor reduction and microcephaly. Dev Biol. 2009 Jan 1;325(1):162-70
Assay type: Immunohistochemistry
MGI Accession ID: MGI:6197789
Gene symbol: Mki67
Gene name: antigen identified by monoclonal antibody Ki 67
Antibody: anti-Ki67 (NCL-Ki67p)
Detection system: Secondary antibody coupled to Alexa Fluor 488
Results
Specimen 2A: embryonic day 12.5 (more )
Note: Double labeled: green - Mki67; red - Tuj1 (Tubb3 assay MGI:6197791).
Structure Level Pattern Image Note
TS20: cerebral cortex Present 2A Expression in both dorsal and ventral telencephalon.
TS20: lateral ganglionic eminence Present 2A Expression in both dorsal and ventral telencephalon.
Specimen 2B: embryonic day 14.5 (more )
Note: Double labeled: green - Mki67; red - Tuj1 (Tubb3 assay MGI:6197791).
Structure Level Pattern Image Note
TS22: cerebral cortex Present 2B Expression in both dorsal and ventral telencephalon.
TS22: lateral ganglionic eminence Present 2B Expression in both dorsal and ventral telencephalon.
Specimen 2C: embryonic day 16.5 (more )
Note: Double labeled: green - Mki67; red - Tuj1 (Tubb3 assay MGI:6197791).
Structure Level Pattern Image Note
TS24: cerebral cortex Present 2C Expression in both dorsal and ventral telencephalon.
TS24: lateral ganglionic eminence Present 2C Expression in both dorsal and ventral telencephalon.
Specimen 2D: embryonic day 18.5 (more )
Note: Double labeled: green - Mki67; red - Tuj1 (Tubb3 assay MGI:6197791).
Structure Level Pattern Image Note
TS26: cerebral cortex Present 2D Expression in both dorsal and ventral telencephalon.
TS26: lateral ganglionic eminence Present 2D Expression in both dorsal and ventral telencephalon.
Specimen 2E: embryonic day 12.5; Rac1tm1Djk/Rac1tm1Djk, Foxg1tm1(cre)Skm/Foxg1+ (more )
Note: Conditional mutant. Double labeled: green - Mki67; red - Tuj1 (Tubb3 assay MGI:6197791).
Structure Level Pattern Image Note
TS20: cerebral cortex Present 2E
TS20: lateral ganglionic eminence Present 2E
Specimen 2F: embryonic day 14.5; Rac1tm1Djk/Rac1tm1Djk, Foxg1tm1(cre)Skm/Foxg1+ (more )
Note: Conditional mutant. Double labeled: green - Mki67; red - Tuj1 (Tubb3 assay MGI:6197791).
Structure Level Pattern Image Note
TS22: cerebral cortex Present 2F
TS22: lateral ganglionic eminence Present 2F
Specimen 2G: embryonic day 16.5; Rac1tm1Djk/Rac1tm1Djk, Foxg1tm1(cre)Skm/Foxg1+ (more )
Note: Conditional mutant. Double labeled: green - Mki67; red - Tuj1 (Tubb3 assay MGI:6197791).
Structure Level Pattern Image Note
TS24: cerebral cortex Present 2G Authors report reduction in expression domain particularly evident starting at E16.5.
TS24: lateral ganglionic eminence Present 2G Authors report reduction in expression domain particularly evident starting at E16.5.
Specimen 2H: embryonic day 18.5; Rac1tm1Djk/Rac1tm1Djk, Foxg1tm1(cre)Skm/Foxg1+ (more )
Note: Conditional mutant. Double labeled: green - Mki67; red - Tuj1 (Tubb3 assay MGI:6197791).
Structure Level Pattern Image Note
TS26: cerebral cortex Present 2H Authors report reduction in expression domain particularly evident starting at E16.5.
TS26: lateral ganglionic eminence Present 2H Authors report reduction in expression domain particularly evident starting at E16.5.
Specimen 3G: embryonic day 15.5 (more )
Note: Double labeled: green - Mki67; red - BrdU.
Structure Level Pattern Image Note
TS23: lateral ganglionic eminence Present 3G
Specimen 3H: embryonic day 15.5; Rac1tm1Djk/Rac1tm1Djk, Foxg1tm1(cre)Skm/Foxg1+ (more )
Note: Conditional mutant. Double labeled: green - Mki67; red - BrdU.
Structure Level Pattern Image Note
TS23: lateral ganglionic eminence Present 3H
Specimen E14.5 Rac1-KO not shown: embryonic day 14.5; Rac1tm1Djk/Rac1tm1Djk, Foxg1tm1(cre)Skm/Foxg1+ (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS22: lateral ganglionic eminence Present Regionally restricted Expresion at subventricular-mantle zone border of lateral ganglionic eminence.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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03/25/2025
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