Tg(CMV-IL4)17Yoska
Transgene Detail
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| Symbol: |
Tg(CMV-IL4)17Yoska |
| Name: |
transgene insertion 17, Yoshie Kametani |
| MGI ID: |
MGI:6197565 |
| Synonyms: |
NOG-hIL-4-Tg |
| Transgene: |
Tg(CMV-IL4)17Yoska Location: unknown
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| Alliance: |
Tg(CMV-IL4)17Yoska page
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| Transgene Type: |
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Transgenic (Humanized sequence, Inserted expressed sequence) |
| Mutation: |
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Insertion
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Tg(CMV-IL4)17Yoska expresses
1 gene
Transgene expresses:
| Organism |
Expressed Gene |
Homolog in Mouse |
Note |
| human |
IL4 (3565) |
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human gene |
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Tg(CMV-IL4)17Yoska expression driven by
1 gene
Transgene expression driven by:
| Organism |
Driver Gene |
Note |
| cytomegalovirus |
CMV |
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Mutation details: The construct comprises the human cytomegalovirus immediate early (CMV IE) promoter, an SV40 intron, the human interleukin 4 cDNA, and the SV40 poly(A) signal. The construct was microinjected into NOG (NOD.Cg-Prkdcscid Il2rgtm1Sug/ShiJic) fertilized eggs at the pronuclear stage. Line 17 showed intermediate expression of the exogenous gene and stable germline transmission.
(J:248533)
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| Mouse strains and cell lines
available from the International Mouse Strain Resource
(IMSR) |
| Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available
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| Original: |
J:248533 Kametani Y, et al., NOG-hIL-4-Tg, a new humanized mouse model for producing tumor antigen-specific IgG antibody by peptide vaccination. PLoS One. 2017;12(6):e0179239 |
| All: |
1 reference(s) |
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Analysis Tools
